Manatee rescue

I went to visit “Dennis” (the 800-pound stranded manatee) yesterday, too. He was chomping on some algae underneath one of the piers, so I got a good view of him from above, but there were too many people there. I didn’t stay long. 

This morning I had family matters to attend to, so I missed the excitement of Dennis’ rescue. Ah yes, he was rescued this morning but apparently did not go all that willingly. You can read more about it here: http://tinyurl.com/4b2xtn.

Well, okay, I admit that I wouldn’t have gone to the harbor today even if I had had the time to do so. I wouldn’t have wanted to have been in the way of the rescue team, and what if something had gone wrong? Eeeeek!!!

My tender heart couldn’t have taken it. As it was, watching the news footage of Dennis being captured and carted off was enough to make tears spring to my eyes. I am such a wuss!

Anyway, I am happy to say that this Caution Manatee sign will probably be taken down now. Dennis is well on his way to Florida.

Manatee on Cape Cod

Early this morning I read about the recent spotting of a manatee, also known as “sea cow,” in Sesuit Harbor, East Dennis. Here is a report about it: http://tinyurl.com/4y9k9q. Well, Sesuit Harbor is just a five-minute drive from my parents’ house. I couldn’t pass up the opportunity. So I grabbed my camera and off I went…there were already a few people holding coffee mugs and walking up and down the docks in the wind and light rain, trying to spot the unusual-looking sea creature.

I joined them and began chatting with one of the marine mammal rescue workers who informed me that this is the farthest north a manatee has ever been observed. She added that her team is going to rescue it soon and take it down to Florida because it would not survive the winter on Cape Cod. The water is just too cold here.

As we were talking, the manatee surfaced right in front of us. A very exciting moment. I got a good shot of it, as you can see. I will go back to the harbor tomorrow…but hope that by then the large gentle creature has been taken to a warmer habitat down south.

Watching Jon Stewart

While waiting for the second presidential debate to begin this evening, I watched Jon Stewart commenting on the recent VP debate. HILARIOUS! I laughed out loud. See: http://tinyurl.com/4ufz8q.

When asked what the VP candidates had to do in order to be successful during the debate (this obviously occurred before the debate took place), media analysts answered that Joe Biden basically had to be a gentleman and avoid appearing sexist.

And Sarah Palin? Well, a CNN senior analyst stated that she had to prove that she can speak in a normal English sentence…(that’s IT???!!!)

And Jon Stewart commented: so to be successful, her standard tonight was the same as a roadside sobriety test. Hehehe!

Okay, the presidential debate is almost on. Less than three minutes to go!

Anti-anaemia drugs may not be safe for myeloma patients

I had time this morning to glance at some older Science Daily articles, including this one, published in mid August, on a drug commonly used to treat anaemic cancer patients: http://tinyurl.com/474ptk. The article begins as follows: A recent study published in American Journal of Hematology demonstrated that Erythropoiesis-stimulating agents (ESAs), a widely used drug to treat anemia, may have a negative impact on the survival of myeloma patients. Yikes.

ESAs are, for instance, drugs like Procrit, Epogen and Aranesp.

I am borderline anaemic but take no anti-anaemia drugs. Never have. But many myeloma patients do take these drugs and should be aware of this Greek study that evaluated myeloma patients over a period of 20 years. Those taking ESAs progressed more quickly and died sooner than those who did not: The median survival rate was 31 months for patients who were administered ESAs, compared to 67 months in those who were not exposed to ESAs. The median progression-free survival for patients in the ESA group was 14 months, and 30 months for those without ESA exposure. Eh.

If I were taking ESAs, I would be concerned enough to quiz my health provider carefully about them. Even if these drugs were given to the sickest patients in the study, i.e., those who would have done poorly anyway, as indicated by a Mayo Clinic doctor quoted in the above-mentioned article, I always think it’s best to err on the side of caution. Just my opinion!

Hanging out

I don’t have any interesting news to blog about these days…just family reunion stuff. My sister was here when my parents and I arrived from Italy last Wednesday, and my niece arrived two days ago from Arizona, where she and my sister live, so yesterday we all got together for the first time in years. Lots of laughing, horsing around and teasing, as though we had never been apart. 

I also got clobbered twice at Scrabble, as expected, but I didn’t do as badly as I thought I would…in fact, at one point I was ahead (my niece was very upset, hehe)…but then she came up with a 7-letter word. Eh! She and my sister know all the cute Scrabble tricks, I still have to learn…

I am staying at my parents’ house on Cape Cod, Massachusetts. The Cape, as we call it, is a lovely peninsula about an hour and a half’s drive south of Boston. I was born on Martha’s Vineyard, an island off the coast of Cape Cod. As I think I have mentioned here before, when I was six years old my parents moved to Florence, Italy, where I grew up (I went through the Italian public school system, including a couple of years at the University of Florence).

Anyway, when I was in my early 20s, I returned to the U.S. and went to college in Cambridge, MA. And I lived and worked in Boston after graduating. So I have strong ties to this area and know it well. Very pretty here at this time of year. I will be taking photos but not publishing them (probably!) until I return to Italy two weeks from now, because I don’t know how to upload photos onto my mother’s computer, a Mac, and, quite frankly, I don’t want to waste my precious time here learning how to do that.

So these are lazy days, spent visiting with my family, watching U.S. television, reading and going shopping (clothes are sooo cheap here compared to Italy!). And today I want to go take a walk on the beach…the Cape has some really stunning beaches. And myeloma? Forgotten, except when I check my blog. Mmmh, sometimes it’s nice to be forgetful…!

Huh?

I know I have been obsessing a bit, ok, a LOT, about the recent VP debate, but I am absolutely infuriated that Sarah Palin was allowed to get away with so many false statements (see La Cootina’s blog for a big one!) and accusations. And with NOT answering questions. Outrageous.

And since when has one of the qualifications for being VP been: don’t say anything TOO STUPID during the one and only VP debate before the election? In my view, this is simply apPALINg.

And here is some more appalling stuff. Take a look at the following excerpt from the VP debate transcript. I randomly chose a couple of sentences pronounced by Sarah Palin:

I think tomorrow morning, the pundits are going to start do the who said what at what time and we’ll have proof of some of this, but again, John McCain knows how to win a war. Who’s been there and he’s faced challenges and he knows what evil is and knows what it takes to overcome the challenges here with our military. Two sentences later, she says, He’ll know how to win a war. 

Huh?

Setting aside the syntactical gibberish, all this “war winning” nonsense is frightening to me…and reminds me of another issue mentioned almost en passant by Joe Biden during the debate, i.e., that McCain wouldn’t even meet with a close NATO ally: Spain. SPAIN? That really stuck in my mind…at the time, I thought Biden must be wrong.

Well, this morning I looked it up. During a September 18 radio interview, McCain was asked if he would meet with Spanish Prime Minister Zapatero and invite him to the White House. In a nutshell (you can listen to the entire interview on YouTube), the GOP candidate responded vaguely that he would be willing to meet with those leaders who are “our friends” but added that he would stand up to leaders who “wish to harm us.” The implication was that Prime Minister Zapatero was among the latter. This bit of news was not well-received in Spain, as you can imagine. Hmmm, and I thought that McCain’s strong point was foreign policy. That may well be, but one thing seems obvious: the word “diplomacy” is not in McCain’s vocabulary.

All this warmongering talk and hollow patriotic rhetoric gives me the heebie jeebies.

Enough!, I say.

The VP debate

I managed to stay awake long enough to watch the entire U.S. VP debate last night. Listening to the comments made by journalists and viewers after the debate and then early this morning, though, I began wondering: “did I see the SAME debate that they did?” It didn’t seem possible. For how it is possible for anyone to assert that Gov. Sarah Palin did “well”? WELL??? Why, she didn’t even answer several of the questions posed to her but instead kept going off on irrelevant tangents, repeating the same things over and over and over again, sometimes even using the exact same words she had used moments earlier. I found that absolutely maddening. And that alone confirmed, to me anyway, that she is not very bright…to say the least.

She sounded like someone struggling with a poorly-memorized series of lessons. Inarticulate, at best. And quite frankly I got sick of hearing her repeat that Obama wants to raise taxes (simply not true). Etc. 

I am sure that she must have appeared “cute” to some viewers, with her little winks and smiles and “you betchas” and “doggone its.” But the truth is, we don’t need “cute” in the White House. We need someone who can actually answer questions and deal with tough issues. 

Do we really want someone like Gov. Sarah Palin in the second highest position in the U.S., just a sneeze away from the presidency? Darn and doggone it, we do not. Just my opinion, of course!

Jet lag

The flight yesterday was long (8 hours plus) but smooth–i.e., no turbulence over the Atlantic and no thunderstorms in Boston when we landed, just a few insignificant clouds…lucky! I read and also played “Tetris” and “Who Wants to be a Millionaire” on the airplane TV screen…ah yes, that was fun (I don’t play computer games anymore, but I used to play Tetris).

How odd to be back in the States…unreal…and I miss Stefano (who stayed at home with the cats) very much, it’s quite bizarre to be here without him, in fact, it would be bizarre to be anywhere without him!…but it’s been great to see my sister after such a long time, and my niece is flying here tomorrow. And it’s so pretty here… 

Okay, I need to go take my quercetin, fish oil and curcumin, then get ready to fight Mr. Jet Lag and try to keep my eyes wide open and my mind on full alert for the VP debate (should be interesting…). So off I go! I will write some more as soon as I get over all this yawnsnoreyawnzzzzz! Ciao!

Getting ready to fly!

Our flight for Boston, Massachusetts, leaves early this afternoon…and thunderstorms are predicted in the Boston area for this evening (typical of my luck: of all the days we could have picked to land in Boston, it had to be during the only possible thunderstorm of the entire week…!!!)…anyway, I have just enough time to squeeze in a quick post. Excellent comments left on my IgE post, thanks!, I will have a look at all the links when I return to Italy around October 20th. Much food for thought.

 

Same line of thinking (?): the other day I read a report by Dr. Ralph Moss (see: http://tinyurl.com/43gmmm) on the overuse of antibiotics that could possibly lead to the development of cancer. I don’t have time now to provide a summary of the article, but Dr. Moss writes that it appears that the more courses of antibiotics a person takes over time, the greater the risk of developing certain cancers. If you are rushed for time, just read the last paragraph.

 

Okay, speaking of rushing, I have to rush off to finish packing now. I will post a little something on my blog in a few days…this time from the States! Wow. That reminds me of something: yesterday, as I was saying goodbye to my students, I told them how much I was looking forward to seeing my sister and niece, that I haven’t seen them in more than two years, blablabla. To my surprise, I began choking up, and tears filled my eyes. Even more surprisingly, they were moved, too (well, perhaps not so surprisingly: Italians…the importance of family…you know…!). So we all stood there in a circle, unable to speak for a few seconds. Cute.

 

Okay, if I want to be on that flight I had better start getting ready! I will be posting but probably not answering too many e-mails in the next couple of weeks (I apologize in advance). Take care, everyone! Ciao! A presto! 

IgE and survival

A blog reader, thank you!, sent me a 2007 study on IgE written by an Italian research team. The full study is available here: http://tinyurl.com/4do9nx.

 

Intriguing, I must say. As a myeloma patient, you tend to read mostly about IgG (my type of myeloma), IgA and IgM…but not much about the other immunoglobulins. I looked up IgE and found that it triggers our body’s response to allergens such as cat dander, dust mites and pollen, and it also protects us from parasitic worms.

 

Well, I’d never even thought of having my IgE levels tested, so I was particularly interested in this study. The “Discussion” part tells us that This is the first study reporting polyclonal IgE levels in a large series of MGUS subjects and MM patients. To the best of our knowledge, it is also the first study reporting an association between IgE levels and Hb, and, even more interestingly, between IgE levels and survival in patients with hematologic malignancies. (“Hb” stands for haemoglobin, by the way.)

 

IgE levels are connected to survival? Well, well. Let’s keep reading.

 

The Italian researchers checked IgE levels in a large number of myeloma patients and MGUS folks and compared the results to a control group in order to determine survival and prognostic factors. They found that IgE levels progressively decreased from controls to MGUS and from MGUS to MM. And patients with high IgE levels lived 2 to 3 years longer than those with low or intermediate levels.

 

They concluded that high IgE levels are positive predictors of overall survival (P = 0.03 and 0.08,respectively) and strongly correlated with hemoglobin values.

 

Problem is, though, that total IgE levels are highly variable in general population, depending on many factors, such as age, gender, race, atopy, genetics, immune status, season of the year, tobacco smoke, and concomitant diseases. Further on we read that the Ranges of normal IgE levels are very variable, and no consensus among laboratories has been reached to define normal and pathologic values. Okay, so that could be a reason why IgE has not been taken into consideration in myeloma patients…until now, at any rate.

 

Another interesting finding: IgE is connected to haemoglobin (Hb) and Beta-2 microglobulin (B2M) levels. The researchers found that a high IgE meant a higher Hb and a lower B2M, and this in turn meant a better prognosisl. 

 

In the Discussion part we find the following titbit: The positive association between IgE levels and survival can be interpreted as an indication that (a) the immune system of MM patients with higher IgE levels is less deteriorated […]. Ah.

 

At any rate, because IgE is an antibody connected to allergy response, the possibility that myeloma patients with allergies such as asthma would be more protected than others in terms of disease progression really (!) got my attention since I suffer periodically from bad attacks of asthma (these attacks have returned, by the way, but I think it’s just because of the change in season from hot to chilly) and other allergic reactions. Hmmm, I thought for a second, have I finally discovered something positive about having asthma and rosacea??? Unfortunately, my hopes were dashed when I read that it is unlikely that allergies play a protective role in myeloma. Bummer!

 

This study is particularly interesting because for the first time ever a group of researchers has found a connection between IgE levels and survival prognosis. The higher those levels, the better off you are. I wonder if I could have my IgE levels tested…just out of curiosity. Or…on second thought…do I really want to know…???