Stefano and I are leaving today for France where we will be spending the holidays…in a region we’ve never visited before. Very VERY exciting! 

Before leaving, I wanted to post a photo of our kitties with a festive look (so cute!), but I’m having a few computer burps this morning, no time to fix them, so I’ll just have to say: Happy Holidays, Buone Feste!!! And may 2019 bring several IL-17 antagonists (!), good health (yessss!) and happiness to all of us! Yaaaay!!!

Take care, everyone! See you…next year! 🙂



I try to focus on my  Prevotella heparinolytica research, I really do!, but stuff keeps popping (or pooping, hehe) up to distract me, such as this BBC article on wombat poop: Wombat poop? Yep!

(Aren’t they just the cutest animals?)

Did you know wombats are the ONLY creatures in the entire world that are able to poop out…cube-shaped poop? They apparently use these small cubes to communicate and attract other wombats. Hmmm. Anyway, yes, a fascinating article, accompanied by photos of said poop, too.  😉 

Another “distraction”: I’ve begun my annual routine of Xmas cookie baking. Every year I make cookies for friends and colleagues. I do enjoy it…it relaxes me…but it takes up a lot of my free time…

In spite of a bunch of different commitments in this period, I have taken a look at my previous blogs on the pesky IL-17. Result: anything that blocks IL-17 is a good thing…well, obviously, if it’s a non toxic thing, such as curcumin. So we need to look more closely at this topic…the IL-17 blocker topic.

Anyway, I’ll try to do some research over the weekend…or…hmmm…perhaps…NOT! 😉

Take care, everyone!

Gut bacteria plays a big role in the progression to active myeloma, according to a new Italian study

One of my Italian blog readers sent me this link today:

I realize the article is in Italian, but hey, you’re in luck 😉 : you can read the full study, on which the Italian article is based, in English…at this link:

In any case, I’m going to give you a brief summary (based only on the article. I need more time to read/go through the full study). Here goes.

Researchers at the Ospedale di San Raffaele in Milan have discovered that a particular type of gut bacteria, called Prevotella heparinolytica, plays a big role in the proliferation of some of the inflammatory lymphocytes involved in the progression from asymptomatic to active myeloma.

Here’s what happens, in a nutshell. First, the pesky Prevotella bacterium activates the above-mentioned pesky lymphocytes. The lymphocytes then wander over to the bone marrow where they help plasma cells proliferate. They do so by releasing an inflammatory molecule called IL-17.

Arianna Brevi, one of the main researchers, points out that IL-17 could become a predictive tool, since it can actually be measured in the bone marrow of asymptomatic patients. In other words, it might be able to show which patients are more at risk of developing active myeloma.

Testing their findings on lab mice, the researchers were able to block IL-17 and other inflammatory molecules involved in the progression to active myeloma. Result: they SLOWED DOWN progression to active myeloma. Incidentally, they used anti-inflammatory drugs that are already on the market.


That got me to wondering if curcumin’s inhibition of IL-17 is the reason, the main reason, why I’ve remained “inactive” for so many years, as have so many of you, too!

Well, well, a VERY exciting finding today!!!

(More research needed, of course…)

P.S. Finally, I just wanted to mention that I’m FINE and have been doing FINE for a while, now. No time for the blog, though. I’ve been busy with life…tons of stuff to do, blablabla. Thanks for your notes of encouragement…much appreciated! 🙂