Curcumin, obesity, diabetes

June 25 2008 post. A group of Columbia University Medical Center scientists lead by Dr. Drew Tortoriello, an endocrinologist, discovered that turmeric-treated mice were less susceptible to developing Type 2 diabetes, based on their blood glucose levels, and glucose and insulin tolerance tests. They also discovered that turmeric-fed obese mice showed significantly reduced inflammation in fat tissue and liver compared to controls. They speculate that curcumin, the anti-inflammatory, anti-oxidant ingredient in turmeric, lessens insulin resistance and prevents Type 2 diabetes in these mouse models by dampening the inflammatory response provoked by obesity. I am now curious to read their results, to be published soon in “Endocrinology.” For now, we can read the Eureka alert:


Very interesting topic. My glucose levels are perfect, but they have always been within the normal range, so I can’t say that I have noticed a huge difference. Yes, a bit lower compared to before, but I doubt there is much statistical significance.


And the link between inflammation and obesity is also interesting: Curcumin administration was also associated with a small but significant decline in body weight and fat content, despite level or higher calorie consumption, suggesting that curcumin beneficially influences body composition.


I am going to try to keep an eye on the work of these scientists because they are exploring novel methods of curcumin administration to increase its absorption, and are also interested in identifying novel anti-inflammatory processes invoked by curcumin and in adapting those processes in the development of more potent curcumin analogues. Yeah!

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