Curcumin and NF-kappa B

NF-κB is a protein complex that becomes activated in response to inflammatory stimuli and has been linked to cancer. It interferes with apoptosis (programmed cell death) and chemotherapy, among other things. Therefore, the inhibition of NF-κB is the target of many cancer studies. Curcumin is one such inhibitor. I found a very detailed study on NF-κB, titled NF-κB in Cancer: from Innocent Bystander to Major Culprit published in 2002, but a friend informed me that it seems to have been taken offline. And I forgot to make a copy of it. Duh. Too bad. At any rate, here is a good substitute, written in 2004 by Prof. Bharat Aggarwal (and I have the full text in my files, so if the link should not work in the future, and you would like to read this study, just leave me a note here):

1 Comment

Leave a Reply

Your email address will not be published. Required fields are marked *