My fall 2010 protocol

See October 18 2010 post. Some blog readers have recently asked me what my current protocol is. So, even though I have no earth-shattering update concerning my daily protocol, I decided to publish a post about it today…One of my super-organized blog readers asked me a series of questions, so the easiest thing to do is to answer them one by one…

Question: What is your current curcumin “ritual” (i.e., do you divide it into doses? do you combine it with bioperine or any other supplements or foods to help bioavailability? do you take it in pill form or as a powder? do you take it before, after or during meals?).

Answer: For a long time now, I have been taking one big dose about an hour before dinner (=16 capsules just of curcumin…). I make an exception if we are having a curry or another Indian dish for dinner: in that case, since I always use heaps of organic turmeric, I take all my capsules with dinner, hoping to increase their bioavailability. What type of curcumin? Well, I take either Doctor’s Best, the 500 mg capsules (which do not contain any silicon dioxide), or NSI, the Vitacost brand (ditto). Both contain bioperine (black pepper extract). By the way, I have eliminated pepper from my diet (not red pepper, of course), just to be cautious…too much pepper could be too much of a good thing!

Question: Please specify your current schedule of other supplements (specifying the exact dosages, the forms in which you take them and the time of day — including whether before, after or during meals).

Answer: right before I take my curcumin capsules, I take 2 grams of fish oil and 1.5 grams of quercetin, all in capsule form (i.e., not caplets or pills or gummy bears). I make sure that the fish oil is molecularly distilled/purified…This is the easy protocol that I have been following this summer, but I should mention that I soon plan to add ashwagandha for three-month cycles. I am a big fan of “less is more,” so I plan to be very careful…

Question: Are there any supplements that you started and then stopped taking due to side effects or other reasons?

Answer: Yes. Details:

-Parthenolide, or PTL (feverfew extract). I will probably never take any more PTL, even though it attacks leukemic stem cells, which is obviously fantastic. You see, I recently found out (see my October 6 2010 post) that it induces cellular protective responses that likely function to reduce its overall cytotoxicity in leukemic cells. That is not good at all, but it also might explain why my PTL experiment (May 2009) was such a failure…

-BCM-95 or Biocurcumax. Sherlock and I tested BCM-95 in 2008, and our myeloma markers worsened…a lot! So, until I am 1000% sure that there is a truly fabulous (backed up by solid proof etc.) new curcumin on the market, I will stick with C3 Complex curcumin, which has been tested in various clinical trials. Case closed.

-Resveratrol. The jury is still out. Back in 2008, I took one of the two best brands available on the market, but my results ended up being only so-so: some markers slightly improved (monoclonal component, total IgG, e.g.), and some got slightly worse (total protein, red and white cell counts, blood viscosity, e.g.). All in all, no dramatic changes, though. I should make the point that I tested resveratrol in the summer. Well, I don’t test anything during the summer anymore. It simply gets too hot here, and, based on what I have been told, I am afraid that my blood tests would not be entirely reliable, since the test tubes sit around in a hot lab for a certain amount of time…blablabla… Anyway, that is a reason I might try resveratrol again…

Ganoderma lucidum or Reishi (the New Chapter brand). I began testing it last spring but had to stop taking it when we left for the UK (=so I still don’t know if it did any good or not…). Reason for stopping: I just couldn’t travel with too many supplements. Now that I am over my bout with bronchitis, though, I plan to test it again, taking the recommended daily dosage, no more. In order to avoid taking so many capsules at once, however, I will take it in the early afternoon whenever possible. I have a huge amount of faith in the anti-myeloma effects of Ganoderma lucidum, so it had better not let me down!

Side effects: no, I have never taken anything that has given me any trouble…not even when my experiments ended up being complete failures.

SUMMARY: Just before dinner (with the above-noted exception), every day, I take 8 grams of curcumin, 2 grams of fish oil and 1.5 grams of quercetin. To that I am soon going to add almost 1 gram of ashwagandha (also known as Indian ginseng) for three months. That is my basic protocol, to which I will add anything I plan to test for a couple of months or so. Next test: G. lucidum (=Reishi). Okay, I think I have answered all of my blog readers’ questions now. If I haven’t, though, or if you have any more, please feel free to ask…

Oh wait, another question that I frequently get asked is: “have you ever had any chemotherapy?” Well, this seems like a really good time to declare publicly that I have never had any chemotherapy or any other conventional treatments (=nothing stronger than antibiotics!).

I also do not have any CRAB symptoms and do not take bisphosphonates. Hmmm, what else? Ah yes, I do not take any multivitamins or, indeed, any individual vitamins, with the exception of vitamin D, which, as I have written countless times, I believe should be on the list of the routine testing/screening of all MGUS, SMM and MM patients (see my Page on myeloma and vitamin D). Every single one of us should have our vitamin D levels monitored. Indeed, all cancer patients should probably have their vitamin D levels tested! 

That’s it, folks!

Afterthought: I have also started drinking a cup of green tea almost every afternoon (if I have the time, that is)…


  1. Hello Margaret,

    I understand that you accept the idea of your friend, Sherlock : Atomic Bomb before the dinner. And I can also understand that you want to take Fish Oil together with Curcumin for better absorption and digestion. Once I read about it regarding to the olive oil.

    But why are you taking Quercetin with them? I mean, why not any other time of the day, why together?

    Isn’t it bad for the stomach and body? Is it really better that way for the absorption?

    I was always thinking of dividing natural supplements should be better instead of taking all of them once and together. It seemed more logical to me…?

    I will be very glad if you answer me.

  2. Margaret

    When I started taking Vit D 50,000 iu 1 a week for 12 weeks as recommeneded by a CAM dcotor. My Ca shot from 2.58 to 2.69 when I re-tested at the 7 week period.
    My myeloma doctor (separate from CAM) told me to IMMEDIATELY stop taking Vit D, and my Ca evels returned to 2.65 withint about 6 weeks, currently.
    My Vit D levels were normal before CAM put me on Vit D

  3. Hallo Magaret,

    Wat kost de curcumine in Italie?
    Misschien kan mijn dochter dan beter wat meenemen
    vanuit daar.

  4. Hello Margaret,

    I was diagnosed in June 2012 with Asymptomatic Myeloma and upon discovering your blog began taking Curcumin. I have been on a 6 grams/ daily regimen for about 5 months and have recently increased the daily dose to 7 grams daily using your once a day bomb theory along with 1.5 grams of quercetin and Cod Liver Oil. My numbers remain stable and I have none of the CRAB symtoms. I eat a healthy diet what I would describe as a Mediterranean diet. Are you still following the same Curcumin protocol? Also, I would be interested in knowing if you consume any alcool?

  5. Thank you, Margaret, for being here…for all of us!!! Questions; why the Quercetin and do you have any advice/thoughts on taking IP6 and Inositol.? Doing fish oil and almost up to 8 grams VitaBreeze Pure Turmeric Curcumin C3 Complex with BioPerine 750mg extra Strength. Thanks in advance for ANY advice.

  6. Hi Margaret,

    After four years of totally drug-free SMM, I’ve now been advised that I’ll need to start treatment within the next few months, due to bone lesions appearing for the first time and fairly significant increases in my M proteins although I continue to feel great.

    As an avid follower of your blog since I was diagnosed, I re-read your Fall 2010 protocol regarding ashwangandha and would like to know if you still recommend trying this? If so, any dosage recommendations.

    I’m hoping to buy enough time to get down to our cottage this summer for a couple of months before beginning treatment or,ideally,stave off drug treatment even longer. I am inclined to add ashwangandha to my neutraceutical protocol.

    Also, search as I might, I can’t seem to locate your current protocol. Can you kindly direct me to it?

    Would really appreciate hearing from you!

    Best Regards,


Leave a Reply

Your email address will not be published. Required fields are marked *