Just briefly…I wanted to say that tomorrow Stefano and I are zooming off for about 10 days (= holiday…yaaaaay!) with a couple of our friends. I don’t know if I’ll have access to Internet during that time, so I just thought I’d publish a quick post.
Well, I hope you’ll have as much fun as I plan to have!!!
Thanks to Karen for providing the link to this incredible story. At first, like other readers, I thought he’d donated his stem cells to try to save the life of a teenager in France, but no, he’d donated his bone marrow.
Still, I’d never heard of anything like this…I wonder if he had an allergic reaction to the drugs…? Anyway, I suppose we’ll learn more in the coming days…
Yesterday I came across a Science Daily article discussing a recent study on the need to have different diagnostic criteria for the kappa and lambda types of myeloma. Apparently some patients with the lambda type go undiagnosed, based on current criteria.
I just read a bit of news that I thought I’d share here on the blog.
A new study shows that exposure (NOTE: “a high lifetime exposure“) to an insecticide called permethrin increases one’s risk of developing MM. This insecticide is used in public health mosquito control programs, for example. Eeeeek!
I already knew about the dangers of drinking very hot tea, and this is confirmed by a new study: it can almost DOUBLE your risk of cancer, esophageal cancer. I read about it a couple of days ago in this CNN article…interesting read, have a look: http://goo.gl/F6jC6N
Here’s an excerpt: “Researchers found that tea drinkers who liked their beverage to be warmer than 60 degrees Celsius (140 degrees Fahrenheit) and consumed more than 700 ml of tea per day — about two large cups— had a 90% higher risk of esophageal cancer, when compared to those who drank less tea and at cooler temperatures.”
According to Stephen Evans, a professor of pharmacoepidemiology at the London School of Hygiene & Tropical Medicine (now, that’s quite a mouthful, eh!), the problem isn’t the type of beverage. The problem is the heat. So basically, anything that’s too hot is dangerous, even, say, microwaved jam (now, why would you microwave jam? Hmmmm…whatever…). I’d add this to the list: very hot soup.
At any rate, since we are already dealing with multiple myeloma in various shapes and forms, I don’t think we need to raise our risk of getting another type of cancer 🙄 (sheeesh!)…And so, just to be on the safe side, let’s avoid eating or drinking anything on the way-too-hot side!
I mean, you try to be oh soooo careful whenever you set foot outside your house, especially during the flu season…For example:
you never go food shopping during peak times
you avoid seeing friends if they have the slightest sniffle
you never shake hands or kiss anyone, or, well, you try not to…
My “try to avoid getting sick” list goes on and on…I repeat, I try to be sooo careful. I always carry a little bottle of hand sanitizer in my purse, for emergencies, such as, well, let’s say that, due to social circumstances, I’ve been forced to shake hands with someone and can’t immediately rush off to find a bathroom and wash my hands, which wouldn’t be very courteous, would it? Sort of like, “Oh, such a pleasure to meet you…um, excuse me, where’s the bathroom?” Much more polite to turn my back discreetly ASAP and whip out the sanitizer, right? And certainly much better than saying, “Oh, please don’t take this personally. I don’t shake hands with anyone because I have smoldering multiple myeloma, and shaking hands with you might kill me.” Hmmm, I wonder what the reaction to that would be! I might try it someday…(just kidding!)
So yes, I try to be super careful, especially during the flu season, as I mentioned before.
But sometimes, in spite of all your precautions, the germs GET YOU anyway. And this time it wasn’t because of my passing next to a sneezing child in the supermarket.
This time it was an IN-HOUSE GERM ATTACK.
Last Friday Stefano came home from work with a sore throat. When he told me about the sore throat, my “GERM ALERT” alarm started blaring loudly, and I avoided touching or going near him all weekend, no hugs, nothing…well, duh, of course we sleep together…
But usually that works…keeping away from him, I mean.
Not this time.
This time the germs he’d picked up were a bunch of really TOUGH guys…
And those tough dudes MIGRATED OVER TO ME, where else?, over to the innocent nice gal with the teeny tiny immune system…
And so, while Stefano merely had what he called a “mild sore throat,” and in fact we had dinner out with friends on Saturday night, here’s what happened to me, starting on Sunday: I woke up with a TERRIBLE sore throat (which, luckily, disappeared within 24 hours…awful, I could barely swallow/talk).
By Sunday evening I had a TERRIBLE cough, ah yes, THAT cough, THE cough. Then fever, vom…well, yeah, that, too. What else? Oh, terrrrrrrible fatigue. I slept and slept and slept, propped up into a sitting position in bed because of THE cough.
Monday was the worst. Then, on Tuesday morning, I began thinking I’d survive. How did I know? My sense of humour came back. 😉
Anyway, since by now I recognize all the symptoms and am well aware that, with my compromised immune system, things can go downhill reaaaaaally fast, from a little sniffle to a full-blown cough within hours, I began taking an antibiotic, a strong one, on Sunday night (but that’s when I was still in vom… mode, so I don’t know how much antibiotic I managed to assimilate…sorry, trying not to be too gross, here!).
Yesterday, much much better: I didn’t have a fever, cough was better, etc. Today I’ve barely coughed at all!
So I’m officially convalescent now, taking it easy, just doing some light housework (laundry, dishes, etc.) but mostly resting, watching my TV series in bed, with various cat-nurses draped on and around me.
But a little while ago I got a call from Stefano (who wasn’t feeling that great this morning but had to go to work…), telling me that he feels terrible. It’s not just a “mild” sore throat anymore. Sheeshhhhh. No idea how he’s going to be this evening, but it doesn’t sound good.
I told you those germs were TOUGH! Mamma mia! But…we’re going to smash ’em to smithereens…no worries.
Anyway, take care, everyone, and stay well!!! Stefano and I will, too! Ciao! 🙂
Some interesting news this morning: for the first time, a group of researchers has reported on the essential role that a specific protein, called Ufbp1, plays in the development and function of plasma cells.
Now, we don’t really need to know all the complicated steps involved in this process…Here’s what’s relevant to us: when Ufbp1 becomes upregulated (that is, when there is too much of it), the development process of plasma cells can go wacky and give rise to allergies, autoimmune diseases, and, tada!, multiple myeloma.
Therefore, if researchers can find a way to manipulate and control the expression of Ufbp1, they might be able to come up with new treatments for all these conditions.
Very interesting, indeed.
In this Science Daily article, the paragraph on multiple myeloma is the third from the bottom: http://goo.gl/zqP5dY
Unfortunately, I don’t have time to read it today, the entire thing, I mean…but I thought that I’d go ahead and post about this discovery, which could, potentially!, have an impact on the field of myeloma treatments…not now, of course, but in the future…
As the SD article states, in fact, this discovery could lead to “the next generation of multiple myeloma treatments,” to which I would add, “preferably (!) a much less toxic generation compared to previous ones…”
How did I let a month, well, almost a month go by without posting even something silly??? Dear me!!!
Thing is, I’ve been super busy, with a million and a half things to do, including some long overdue house improvement projects, which have been taking up a lot of my time, especially since Pandora, = one of the two incredibly adorable kittens we adopted about a year and a half ago, simply loves to, er, HELP me. She follows every move I make, and often intervenes. And so, thanks to her, a task that should ordinarily take only one hour to complete can take up to two hours…Of course, she’s such an entertaining little creature that it usually doesn’t matter…She does make me laugh!
So yes, all is well, yes indeed, all is well. I have been, and AM, absolutely fine and dandy.
Now, before I go back to a task I must finish before Stefano gets home from work, I wanted to let you know that I hope you haven’t tried to get in touch with me using the blog’s “Contact” form. That form hasn’t been working for ages. There are, however, a couple of easy ways you can get in touch with me (if you don’t have my email address, I mean):
My blog’s Facebook page (just look for Margaret’s Corner, living with smoldering myeloma). Send me a private message there. I will respond as soon as possible, within a day or so, at the most, unless I am on holiday or without access to Internet for some reason.
You can also leave a comment on the blog…on any post, even an old one. If you wish your comment not to be published, just ask me not to approve it, although often that is quite clear to me, and I respect my readers’ privacy. That way, I (and only I!) will have your email address and can reply to you.
Okay, I think that’s about IT for now! I do hope everyone is doing well, VERY well!!! Take care! Ciaooooooo!!! 🙂
Lately, I’ve been so caught up with stuff to do that I haven’t had time to post anything, not even a simple, quick post about our recent long weekend trip to London, which mainly turned into a Harry Potter tour (see last photo…and yes, I stood in line for about a half hour so that Stefano could take a photo of me waving a wand at Platform 9 and 3/4, King’s Cross station; I now am also the proud owner of a lovely Gryffindor scarf, currently my most precious possession 😀 ).
Note: we also met with a good British friend of ours AND visited a couple of museums. OThe best, though, was our tour of Westminster Abbey that included the Queen’s Diamond Jubilee Galleries, which were opened to the public less than a year ago after having been locked up for 700 years! How about that…
These Galleries are located in the medieval triforium, 52 feet above the Abbey’s floor (great views of the Abbey from up there, as you can imagine!!!).
In addition to the views, there are many fascinating artifacts to be seen in this lovely four-chamber “attic,” such as Queen Elizabeth I’s corset (no kidding…I couldn’t believe my eyes, either…)…but the thing I enjoyed the most was walking among the glass cabinets displaying the wooden effigies of dead kings and queens, some still with painted faces, eyes staring into space. Yes, rather eerie, but oh so interesting.
As I recall, the effigy custom began in the Middle Ages and lasted until the 18th century. In short, the fully dressed (wigs included) wooden effigies of dead monarchs were placed on top of their coffins for the funeral processions. I’d never seen anything like it…
So yes, lots of things to look at in the Galleries, including Mary II’s 17th century coronation chair, covered with graffiti carved by Westminster schoolboys and visitors in the 18th and 19th centuries…Hah, this happened even back then, eh!
Unfortunately, no photos allowed in the Galleries (when I found that out, my expression pretty much mirrored that of one of Westminster’s stone dragons, see photo no. 2, above), but, no worries, you can find heaps of photos online.
Anyway, let’s set London aside for a minute.
I’ve been looking (again!) into how our circadian rhythm can affect how we absorb certain supplements. This is certainly not the first time I’ve posted on this topic…In fact, I just re-read my November 11 2007 post, which deals with a study linking circadian rhythm to chemo drug absorption. That is, an important factor in the administration of chemo drugs should be time of day…I wonder how many hospitals take circadian rhythm into consideration…?
Anyway. It seemed logical to me, even back in 2007, that the same would apply to anything we swallow, including our supplements, of course. Aspirin, e.g, is best taken in the evening, when it will not do as much damage to the lining of our stomach.
So there’s lots to be said for the circadian rhythm. I’m reading some more recent studies on this topic, but boyohboy, some of the jargon makes my brain go into DEEP sleep mode. I must persevere, though, because I might just find a pearl buried somewhere…
Has anyone done any research on this topic? I’d love to hear from you!