An aching back and more photos of Venice…

P2030378P2030395Well, my silly little Venice fever lasted about 24 hours, not much longer…no big deal.

But then, on Wednesday afternoon, for no apparent reason (I mean, I hadn’t been hauling around heavy bookcases!!!), I was suddenly struck by a terrible pain in my lower back. I haven’t had that sort of pain in ages…years, methinks. Of course, one of the first thoughts that popped into my mind was: MYELOMA!

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But then Reason took over, and I remembered that I’d had lower back trouble/pain since I was a rather young thing. It’s just that I haven’t had it in such a long time…and I’d forgotten how crippling it can be. That’s all. P2030203

And then I remembered that I hadn’t taken any curcumin since Friday…A FULL FIVE DAYS PLUS WITH NO CURCUMIN…So I got back on curcumin immediately, et voilà!, today I’m feeling much better. Working and up and about. 

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Just being careful when I have to stoop. Little Prezzemolo didn’t understand why I didn’t bend over to pet him this morning, as I usually do. 🙂 

Now, about those five full days without curcumin, I noticed something else that might be connected (or not): my urine was foamy on Sunday night. 

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Foamy is not good, as we know! Anyway, point is: it remained foamy until I got back on curcumin. And now it’s perfectly clear again. A mere coincidence? Probably!IMG_4702

And that reminds me. It’s been a long time since I’ve had blood tests. Way too long. Must go. Soon. 

But not today. My back is much better, but I have a TON of work to do. I need to get cracking, in fact! But I did want to post a few more of my favorite photos of Venice, including that glass puffin I noticed in a Rialto store window, how about that? (Well, okay, it’s a toucan, NOT a puffin, but I like to think of it as a puffin…And you should have seen the puzzled looks on the faces of Venetian glass shop owners when I asked them if they had any glass puffins, hehe…)

Have a super weekend, everyone! 🙂

Venice in the pouring rain…

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Well, this surprise weekend trip came at a slight, er, cost. An unforeseen one. Let’s see…The best thing to do is start at the beginning.

We left for Venice on Friday afternoon, after work, and arrived there around dinnertime. We stayed in a lovely little 3-star hotel (for which Stefano had found a lovely little discount online!), which was about a five minute walk to Piazza San Marco (St. Mark’s Square). Perfect location. Friendly, helpful staff, nice breakfast. Things were looking good. 

On Saturday morning we awoke to the sound and grayness of rain. It was only drizzle at that point. But we’d been smart (or so we thought!): we’d checked the weather forecast and knew it was going to rain on Saturday, so we’d had packed our Skomer island, puffin-watching rain gear. Covered from head to toe, no worries! (Again, so we thought.)

IMG_4722By late morning the annoying drizzle (see gondola photo no. 1) had turned into a downpour, so much so that the hotel receptionist told us (later) that she hadn’t seen anything like it in all the years she’d been in Venice. It was chilly, too, and, as if that weren’t enough, in the afternoon the wind picked up…in Piazza San Marco, especially. Everywhere you looked there were frantic, wet tourists trying to hold onto their useless, mangled umbrellas (by the way, many of those broken umbrellas ended up getting dumped on the streets, which really irritated me…Please don’t litter…ever!!!).

P2020003Consequences for me: some rain managed to get inside my Gore Tex trekking shoes, the ones that have been through terrific downpours on all sorts of terrain in the UK and have always kept my feet warm and cosy. Always. But…not this time. This time my feet got cold and wet, and so they remained…throughout the afternoon and evening. The truth of the matter is that I was so happy to be in Venice that I didn’t really pay much attention. But by the time we returned to Florence on Sunday night, I had developed a fever, not a super high one but enough to make me sleep all day yesterday and keep me in bed part of today as well. I’m much better now, though, and I actually went back to work this afternoon (so much to do!)…from home, of course!…Translations…

IMG_4667Bottom line (an expression my Dad hates!): don’t ignore wet, cold feet! 

Anyway, getting wet and chilled to the bone and developing a fever was bad enough…but that wasn’t the worst thing. And no, we didn’t fall into a canal! 😉

On Friday night, you see, as soon as we’d arrived in Venice, parked our car at Piazzale Roma and hopped on a vaporetto (a sort of Venetian waterbus), Stefano realized that I’d grabbed my OLD camera, not my BRAND NEW one, the one with the super zoomy lens and so on. Oh noooooo!!! We’d been in such a hurry to leave Florence that I hadn’t even noticed. 😯 You have no idea how incrrrrrredibly stupid I felt…Later on, though, as we will see, I was elated at having made that mistake. But not at first, let me tell ya. I mean…in Venice with my OLD camera and, to boot!, with the batteries and accessories for my NEW camera, which of course wouldn’t work for the old one. Terrrrrrrible.

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Oh, but the worst was yet to come: on Saturday afternoon, after the first prolonged downpour, Stefano’s camera simply shut off. Poof. Wouldn’t turn back on. We took it back to the hotel, dried it off and waited. But it refused to work again. In a nutshell, too much water had gotten inside, so the only thing was to wait for everything to dry out and hope for the best. 

So Stefano didn’t have a camera. Correction: Stefano didn’t have HIS SUPER DUPER CAMERA. He was simply devastated, in shock…our vacation–ruined. Nothing like this had ever happened to us, no matter how MUCH it had rained…

And then, almost immediately afterwards, my camera did the exact same thing. It simply turned off and died (it’s still dead, by the way!). And that explains WHY I was RELIEVED, in the end, at not having brought my NEW camera. It’d would be dead, by now…and I’d be in a mental hospital, probably. 😉

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So there we were…in Venice…during Carnevale…with wet shoes and without ONE bloody working camera. An unbearable thought. So I took action. In the late afternoon we went to a camera shop recommended by the hotel folks, where I explained what had happened and asked for a digital WATERPROOF camera, the sort that you can even use underwater. We ended up buying a small waterproof Olympus. It isn’t top of the line, but it was within our budget…sort of…

Most of my Venice photos have therefore been taken with the not-so-great-but-better-than-nothing! camera. As for Stefano, well, I’m very happy to report that, after drying out overnight in the hotel room, his camera began working again on Sunday, which, as all the weather reports had promised, was a splendid sunny day…

Apart from those “small” annoyances, we had a very nice time. I mean, how can you NOT have a nice time in Venice?

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It’s a magical city. Unique. Romantic. Beautiful beyond words, beyond comprehension. Yes, even in the rain and cold. The wonder of getting lost (because you WILL get lost, and that’s part of the magic) in Venice’s narrow winding streets called “calle,” then suddenly entering a small “campo” (= public square), going over the bridges and peering down the canals, at the gondolas…And the Grand Canal, wow…You feel as though you’ve been catapulted into a different world. And I suppose the only good thing about the awful weather on Saturday is that there were very few people out and about…just a few crazy nut cases like us. On Saturday, because of the weather, all the special carnival events had been cancelled. So we almost had the city to ourselves…

But on Sunday…Well, Sunday was an entirely different story. It was a lovely sunny day (as you can see clearly in the last photo, taken in Piazza San Marco of a group of masked ladies with brilliant, rather outrageous outfits), and the masked crowds were out and about, smiling and strutting around, waiting to be admired and photographed. But that part of my story will have to wait, because it’s late in the day now, and I’m getting hungry…Ciao! 🙂

Venice!

Stefano and I have been together for a number of years, and I think I know him quite well, but he can still manage to surprise me. 🙂

A few days ago he suggested we go to Venice this weekend. Just like that.

Venice??? Wow. We haven’t been there in ages…since we were a brand new couple, in fact. Our first, official trip together as a couple was to Venice…and boyohboy, you can’t beat Venice for romance…

Besides, neither of us has ever been to Venice during the carnival period, even though we both grew up here in Florence…

And so, after wondering if we could afford it, I said an enthusiastic “YESSSSS!!!” 

Well then…it’s settled. We’re off to Venice…leaving tomorrow (Friday) afternoon after work and returning to Florence and our kitties (who will be well taken care of, as usual!) on Sunday evening.

VERRRRRY EXCITING!!!

Tons of carnival-related events are going to take place this weekend in Venice (for those interested, here’s the official Carnival in Venice 2013 website, in English: http://goo.gl/2kBMR), such as the contest for the best mask right in Piazza San Marco, which should be fabulous…and offer some super photo opportunities, I hope… 

But today I have to get down to work…Soooo…Ciao for now! 🙂

A Johns Hopkins doctor’s enthusiasm for curcumin…and a bunch of other stuff…

Well, the last few days have been a mix of ups and downs. One of my longtime myeloma friends died. I didn’t even know that she wasn’t doing very well. So yesterday, when another MM friend wrote to me, giving me the news of Carol’s death, I was totally shocked…and upset, too…goes without saying. I’m going to miss you, Carol. Gentle hugs!

I’ve also been working quite a lot. In addition to my regular jobs, I’ve also just been assigned a long translation from English to Italian. It’s a company safety manual, which I have to translate for the company where I work here in Florence. 😯

But all work and no play would certainly make Margaret a dull gal, so tomorrow morning Stefano and I are going bird watching at the Parco della Piana, and in the afternoon I’m getting together with some of my crazy (in a good sense, of course!) girlfriends for some laughs and fun. It’s the weekend, after all!

Now for a few interesting things I’ve come across recently. This curcumin “alert” took me to an interview with a Johns Hopkins doctor who has become very interested in curcumin: http://goo.gl/mg66s Water-soluble curcumin, huh? Mmmh…perhaps that isn’t such an impossible dream after all… 🙂

This Science Daily article tells us that qigong can reduce symptoms of depression and improve quality of life in women undergoing radiation treatments for breast cancer (and I bet it can do the same for many other cancer patients, too): http://goo.gl/qqppm Good stuff! 

My longtime blog readers know about the mutant gene p53. I’ve written quite a lot about it (please use the blog’s “Search” box to find out more). Well, here, in this article, we have something “new” (though, to be quite honest, years ago I had already figured out that targeting mutant p53 would be an incredibly good idea, duuuh! But now we do have more proof to substantiate said targeting, I suppose…sigh…): http://goo.gl/2hbVQ

And finally, an article on curcumin and mistletoe (and their effects on pre-diabetes and liver damage and cancer): http://goo.gl/CKCJ8 I’ve read about mistletoe before but have never really researched it thoroughly. In fact, if you take mistletoe, would you mind getting in touch with me (in private, too)? Thanks a bunch! 

Okay, back to work a bit before dinner…

Have a great weekend, everyone! Ciao! 🙂

Work work work!

IMG_0364Just got back but already overwhelmed with work…translations…and stuff I need to do for my second (online) job…blablabla…But I hope to be able to do some research, too, at some point soon. I have a few studies, drafts…I just need to find some time to have a look at ’em all…

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In the meantime, I thought I’d quickly post some of the photos I took with my new (Xmas!) camera while I was in the States. Just a few, random photos of this and that…for example, two cute dogs that Stefano, my cousin and I saw in Salem, Massachusetts…our Xmas tree, a nuthatch looking for food on a tree, a “Keep Calm” sign I saw in a shop window, a couple of seals off our beach and my parents’ Myeloma buddies (dear Paula…much missed…)… 

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Enjoy! IMG_0156

 

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Back home…and jet lagged…

IMG_0459First, let me apologize for not having written in such a long time. The week I spent with Stefano on Cape Cod went by so incredibly quickly…And then, poof!, we were back in Florence (on Sunday, late afternoon) and were both hit by jet lag…big-time, this time! 

The best thing about coming home was seeing the cats again. What a joy! They were all over me, except for my eldest, Puzzola (13 years old, more or less). When we arrived, she went to her usual corner in the kitchen (being the eldest, she has the privilege of eating “alone”; the others have their own separate but not-so-private eating areas in an area of our dining room…) but ran away whenever I tried to approach her. It broke my heart, let me tell ya, especially when I saw Stefano petting her. She just didn’t seem to recognize me. Luckily, it didn’t last very long. After dinner, Puzzola jumped onto the table (not that we let our cats onto the dining room table, of course! Uhm…) and rushed right over to me, as she always does…And that was THAT! 🙂 IMG_0432

Coming home to heaps of laundry, an empty fridge, 1300 unread emails and so on…But it’s not all bad. I have already planned a get-together with my girlfriends…as soon as one of them gets over the flu (yikes!), that is. And even going back to work (yesterday) wasn’t too “traumatic” (in spite of the jet lag, I mean): all of my students were absolutely overjoyed and welcomed me back with hugs and kisses…I just hope none of them have the flu!!! Don’t you just hate it when people kiss you, then have a terrible coughing fit? Yeah. Exactly. 🙁 

Anyway, things are a bit of a blur right now (I need a few more naps!), and I have quite a lot of work to do. Plus, Prezzemolo has had a recurrence of his feline viral rhinopneumonitis. As with humans, the herpes virus is “reactivated” in cats during periods of stress. 

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And I’m sure that Prezzemolo was very much affected first by my “disappearance” a month and a half ago, then by Stefano’s departure almost two weeks ago. Prezzemolo hasn’t yet fallen in love with our fabulous cat and house sitter (a good friend who adores our cats), and that, I think, was the main source of his di-stress. 

Our friend told me he’d begun sneezing on Saturday. And his nasal discharge…yuuuuuck! I immediately began giving him some immune boosters, including fish oil (for cats), hoping to avert disaster, but when I heard him coughing yesterday morning, I decided not to wait on the antibiotic. So he’s now on a 12-hour antibiotic. Bummer. Poor dear. But really, he seems fine…very active, voracious appetite…the terror of the house…chasing the others and so on…

Speaking of Prezzemolo…It’s only day 3 in Florence, but I’ve come to realize that we’ll never be able to have friends over, ever again. 😉 Prezzemolo, as his name suggests (in Italian, the saying goes that if you are like prezzemolo, = parsley, you pop up everywhere, all the time…), is, well, everywhere…all the time. No matter what you’re doing, even if it’s the most BORING thing (from a cat’s point of view, of course), he has to be right by your side to check it out…On the kitchen counter, in the kitchen sink, on the dining room table, on the stove…you name the place, he’s there. So curious! All this is very cute right now, but I imagine it will be a bit less cute when I have to bake something…and when friends come over for dinner. Nothing like a nosy cat sticking his wet nose into your dinner plate…hmmm…  😉

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Anyway, all is well, more or less. But I miss my parents and the Cape. Eh.

Speaking of the Cape, here are a few of the photos I took with my fab new camera during my stay, including one of me standing in the snow (I love taking quirky photos…This one shows my very distorted reflection in one of the Xmas ornaments I put on my parents’ trees …). I wasn’t able to download any photos onto my Mom’s computer, so I have quite a few that I would like to publish in the next few days…Hope you like ’em!

Take care, everyone!!! 🙂

Sweet!!!

Stefano arrived in Boston yesterday evening. I met him at Logan Airport and screeched a bit too loudly as soon as I set eyes on him…startling a few of the people around me, I’m afraid. 😉 And then we hugged and hugged and hugged, as though we hadn’t seen each other in years.

It’s really hard to explain. Stefano is not just my life partner and my sweetie…He’s my soul mate, my best friend, a part of me. And, while we’re two strong and independent people, no question about that, we share the same interests and hobbies (bird watching, e.g.), and we enjoy each other’s company very very VERY much. Ok, enough, enough…I guess I just wanted to say that it’s reaaaaaally sweet to be reunited… 🙂

Well, we have heaps of things to do today, including planning what to do next week…before we return to Italy, that is. Stefano wants to visit Salem, Massachusetts, and I want to go to Nantucket. So we’re going to see if we have time to do both.

Anyway, I just stopped by to write a quick note for the blog…And now I’ve got to dash off and begin all the planning! And do a bit more hugging, too, as soon as he wakes up!!! 😉

A new gadget and some serious research on xanthones…

First, the funny bit (funny to me, anyway!). Before I left for the States, Stefano and I decided to buy ourselves (well, it’s for me, really…he already has an iPad) a mini iPad. He’s been bugging me for ages to get an iPad, so that I can download and read virtual books instead of filling up the house with real, dust-accumulating books. But I’m a bit old fashioned and sometimes resistant to new, high-tech gizmos. Plus, when I was an undergrad at Harvard (quite a long time ago!), one of my many jobs involved putting books back on their shelves at Widener Library (= book shelver, yes). Ah, how I loved that job…the smell of books…getting lost in the stacks…In fact, that’s when I began dreaming of becoming a librarian (still a dream!)… 😉

Anyway, point is: because of my stubborn opposition to downloading books onto any sort of gadget, I’d refused, till recently, even to contemplate buying anything containing the word “pad.” But I finally gave in…Stefano can be very persuasive, you see!

So as soon as I arrived in the States, about a month ago, I went to a local Apple store and got on a mini iPad waiting list. Yes, a waiting list. The pre-Xmas sales period is not at all a good time to buy a super popular item of any sort. So (to make a long story longer!) I finally called the online Apple store and asked for an “in-store pickup” anywhere in the state of Massachusetts. It turned out that the closest Apple store that had a mini iPad for sale was in Braintree (= the South Shore Plaza mall, for those of you who live in MA). That’s more than an hour’s drive from here. But, no biggie. So a couple of mornings ago I set off for Braintree, which is just south of Boston. 

I didn’t intend for this part of the post to be so long. Okay, I’ll shorten it, even though, wowsers!, I’d never been inside such a HUGE mall…unbelievable (mmmh, loved the “games for the brain” store! 😉 ). Anyway, the upshot is that I got my mini iPad. When I brought it home, though, it refused to connect to my parents’ wireless network. Stubborn little creature, I thought, a tad annoyed.

But yesterday I finally got it to work. So last night I decided to send Stefano an email on the mini iPad…from my bed…what a thrill!

I began typing a message in Italian. Well, let me tell ya, the auto-correct feature went absolutely mad. With hilarious results, I must say. Here’s an example: one of my standard emails greetings for my Italian friends is “cucu!!!,” which is related to the cuckoo clock and is used as a joke (in Italy, when you come out of a hiding place, e.g., you can say “cucu!” like the bird popping out of the cuckoo clock). So I wrote “cucu,” which of course Mr. English Auto-Correct changed to “cucumber.” Cucumber??? And that was just my FIRST word! 🙂 For those who know Italian, the below list should be amusing:

  • “Qualche” became “quail he.” Qualche means “some, a few.”
  • “Questo correttore automatico” became “question correct tore automatics.” Correttore automatico means “Automatic Corrector.”
  • “Almeno ti fai una risata” became “lame no ti fai una roast a.” Almeno ti fai una risata means “At least it’ll make you laugh.” Roast a WHAT? 😉
  • When I reread the message and began laughing hysterically at the “corrected” gobbledygook, I wrote “da schiantare dalle risate,” which became “da Schiaparelli dale rip sate.” Da schiantare dalle risate literally means “It’s so funny it will make you die laughing.” “Schiaparelli”??? Is that even ENGLISH? Oh, okay, just looked it up: Elsa Schiaparelli was a famous Italian fashion designer. Uhm…
  • “Pensa un po’ te” became “Pensacola te.” Pensa un po’ te means “Fancy that!” (hehe, indeed!)
  • And just one more: I wrote that I was laughing like a mad woman, “sto ridendo come una pazza furibonda.” Well, the auto-correct feature translated my comment as “I’m laughing like a mad piazza” (a mad city square???). 😀

Okay, enough. Let’s get serious now. I ran across an interesting item recently. Has anyone ever tasted a mangosteen? I haven’t, I admit. I have never even seen one in real life. It’s a dark purple tropical fruit (nothing to do with mangos, though) that contains heaps of antioxidants and, quelle surprise (not!!!), has been used for ages in traditional Southeastern Asia medicine to treat a variety of ailments, from skin rashes to bladder infections and irritable bowel syndrome.

Recent test tube studies have shown that its compounds, called xanthones, possess antibacterial, antifungal and antiseptic properties. These xanthones are extracted from the thick, hard mangosteen rind (= the pericarp).

So why am I writing about mangosteen xanthones today? Because they also seem to have anticancer activity. Yup. Even more interestingly, they have been found to kill HL60 leukemia cells. In vitro, anyway. See this 2004 Japanese study: http://goo.gl/nfmne And this 2009 Chinese study, on a different leukemic cell line: http://goo.gl/dlzEX And there is also a 2008 French study, on cells from B-CLL patients: http://goo.gl/QyG5E These in vitro tests resulted in the death (= apoptosis) of all the cell lines. Aha! By the way, there are a few other mangosteen-leukemia abstracts on PubMed…

Now, I don’t have much time right now, as you know, so what I have isn’t much: it’s simply the result of a very quick, preliminary, superficial bit of research. That said, I decided to introduce the subject anyway, thinking it might be of interest to some of you. I should also mention that I came across a warning for patients undergoing chemo treatments. If you fall into that category, then don’t even look at a mangosteen or its extracts. It might lessen the toxic effects of the chemo, which would defeat the purpose, of course. I wrote “might” (the conditional tense) because, as usual!!!, we simply do not know…no studies on that topic. Sigh…

Well, that’s it for today. I hope you’ve enjoyed this bit of silliness…AND the mangosteen info, too, of course! Have a super weekend, everyone! 🙂

Happy Happy Happy!!!

Sweet 2013I loved this photo, which I found on Internet. Yum yum! Purrfect!

Well, it’s going to be 2013 in Italy in about a half hour. I’m getting ready to Skype with Stefano so we can bring in the new year together…Off I go!

Have a lovely New Year’s Eve and Day, everyone!!! Ciao!!! 😀

Yes, I’m a real person!!!

This morning a new blog reader’s message gave me quite a chuckle, so much so that I decided to share it with you all…Mainly, though, it gives me the opportunity to clarify a few points…First, though, here is the email:

I have myeloma and only recently came across “Margaret’s Blog” while researching curcumin.  The blog looks fantastic, with so much information.  I’d like to know who Margaret is, or how this got started.  Is Margaret a real person??  If so, I can’t imagine how she replies to all these questions nor how she has time to look up all these articles.  A little background please.  Thanks!!!

I replied to this message, of course, telling the new reader to scroll down my Pages on the right and click on “Living with smoldering myeloma.” The info therein needs to be updated (I’m now 51, not 49 years old, e.g.!), but it does provide a bit of background for those who haven’t been reading my blog from Day One. Another Page that new readers might want to check out is “My discovery of curcumin.”

Here’s the thing: back in 2007, when I first began blogging, I never imagined that I would come across so much information about non-toxic anti-MM substances. Not in my wildest dreams. I also never thought that my blog would become so big…to the point of being unwieldy, I know I know I know! Or so popular, to be super honest. 🙂 So those two above-mentioned Pages were linked to each other. But that was BACK THEN…when I had only created a few Pages and had no idea that I would be creating any more. Hah.

Now, I would like to reassure everyone that I am indeed a REAL person. I’m married to my best friend, a sweet generous loving talented tall dark handsome Italian genius whose name is Stefano. We have been together for, uhm, 15 years or thereabouts…married for more than 13 years. Our six cats fill our lives with joy (and a bit of asthma, too…turns out I’m allergic to cats! Oh well!).

I have three university degrees (B.A., M.A. and Ph.D….not in the scientific or medical fields, though! 😉 ). I’ve always been a bit of a nerd…I love studying and learning new things. Always have.

And I love teaching (Italian or English). For the past five years (plus) I’ve been teaching English in a company in Florence, Italy, where I live now but where I also grew up (I’m one of those odd, purrfectly bilingual creatures…). I’ve recently also accepted a part-time, online job that has to do with English grammar. In my free time (!!!), in addition to doing research/writing for my blog, which means A LOT to me!!!, I get together as frequently as possible (at least once a week) with my fabulous, funny girlfriends…

I also enjoy cooking, reading, and watching good movies or “Downton Abbey”…and traveling (whenever economically possible…) and birdwatching with Stefano. Yes, I do indeed have a busy life. And it’s not always peachy, let me tell ya…My in-laws’ health has been steadily declining in the past few years, for example. And my parents have also had a few health-related issues. But, in my blog, I prefer to focus on the positive aspects of my life, which are many…Overall, I’m a lucky gal, a verrrrry lucky gal! And for me, the glass is always half full…Always!

I’m currently visiting my parents who live on Cape Cod, in Massachusetts, U.S.A. It finally snowed last night…So this morning, as soon as it was light enough, I went outside in my jammies, coat, boots and hat to take a few photos. That was such a glorious, happy moment for me. And in fact that is one of the positive lessons that myeloma has taught me: it’s the small things in life that bring the most happiness…like being out in the snow for the first time in years…

Yesterday I found a funny little item on Facebook (where my blog has its own Page, by the way). As follows: “Today I will live in the moment…Unless the moment is unpleasant, in which case I will eat a cookie.” My mantra. 🙂

A HAPPY, HEALTHFUL NEW YEAR TO EVERYONE!!! 😀