Trying to do some research…

…and failing miserably, I should add (add to the post’s title, that is).
But this time it’s because of something positive, VERRRRRY positive.
Our (now) eldest cat, Piccolo, is definitely feeling better. He’s not out of the woods yet, but, e.g., yesterday, while we were having lunch, he suddenly showed up in the dining room, followed closely by his little black shadow, Prezzemolo (our youngest). He’d been refusing to come downstairs ever since we got back from the vet hospital, you see…
This seemingly small event was a HUGE event in our household, one that made us beam with happiness for the first time in days (we lost our eldest cat last Monday and have been absolutely miserable…)…I rushed into the kitchen to get Piccolo a treat…and a treat for the other cats, too, of course!!!
Today Piccolo has been downstairs twice. Boy, I hope this positive trend continues!
But what, I hear you ask, does that have to do with my research (post title)?
Well, in the past few days, whenever I go into my study, Piccolo follows me and gets up on the desk, using the cat tower hammock (see photo no. 2) to hoist himself up.
Once on the desk, he always positions himself between me and the keyboard, staring lovingly into my face. When he’s tired of being scratched behind the ears and cooed at, he lies down on top of the keyboard and/or the mouse.
Eh!
There’s no way I can do any work at the computer with Piccolo in the way, as you may be able to tell from these photos.
And so…no research.
Oh well, I guess I can take a break, although it seems like ages since I last wrote a proper research post…But tomorrow is my birthday, and I have plans to do absolutely…nothing…Just a romantic lunch out with Stefano up in the hills around Florence…
Tomorrow, by the way, I’m turning 56, an age I never thought I’d reach after finding out I’d progressed from MGUS to SMM in the fall of 2005.
That was almost TWELVE years ago, though, and hey, I did make it to 56, beating the statistics…
And I also plan to keep on going…at least for a while!!! šŸ˜‰

Coffee drinkers, rejoice!

Ever since our beloved cat, Puzzola, died, I’ve been bursting into tears now and again for, well, really, for the dumbest things.
Yesterday morning, for example, as I was preparing my cappuccino, tears began streaming down my face because I realized that I would never be giving Puzzola a pill again. That was the FIRST thing I did every single morning–give Puzzola her hyperthyroidism pill.
Stefano noticed, came over, and held me close. He said, with a broken voice, “it’s because of the pills, right?” He knows me so well…
This morning it was time to change all the cat litter boxes, but after changing the ones in the upstairs bathroom, I had to stop and wait for a while before changing the downstairs one that Puzzola had used for the last time on Monday morning…I’d watched her gather all her strength to go into that litter box…and shortly thereafter we took her to the vet hospital…her final journey…oh boy…so hard.
And here I was, this morning, agonizing over the stupid litter box, as though I didn’t want to cancel all the traces of my Puzzola…silly of me, I know, because of course I clean the boxes at least twice a day, so there wouldn’t have been any Puzzola pee in there anymore, anyway…
But…there you go.
It’s the small, silly, everyday stuff that gets to me. Or friends calling to say they’re so sorry…that will set me off, too.
Stefano is in a lot of pain, too. This was his first cat, you see. Not that it makes it any easier if it’s your second or third or hundredth cat…!!!
Yesterday I read some stuff online about how to cope with the grief of losing a cat. And it led me to a post written by someone who’d had to put his cat to sleep, like us: goo.gl/3mKHAa The post makes a lot of good points, including this one: ” itā€™s about time we recognise the value, depth and integrity of many peopleā€™s relationships with their pets, and the veracity of their bereavement.” No kidding. Cats are part of the family. Period.
Anyway, today I’m feeling a bit stronger. And in part that’s because Piccolo is doing MUCH better (see photo…he looks a bit grumpy because I just woke him up).
He’s finally coming onto our bed in the evening, purring and looking for love and pets…In short, he’s almost back to his usual self.
When he was feeling poorly, in pain, he’d stopped “talking” to me. But in the past few days we’ve resumed our chats, which basically go like this:
Margaret: “Hello, my beautiful boy, how are you feeling?”
Piccolo: “Rau rau rau.”
Margaret: “Rau rau rau? Oh, that’s wonderful, sweetheart. Would you like some food?”
Piccolo: “Mao mao maooo!”
Margaret: “Mao mao maooo, okay. I’ll go get some. Rau!”
And so on.
I say “rau rau” and “mao mao” a lot, these days… šŸ™‚
Oh, and he isn’t lying in the litter box anymore, which is a HUGE relief.
The only thing that worries me slightly is the fact that he doesn’t want to go downstairs. He sits at the top of the stairs and looks at me down on the landing, but he won’t budge. I’m not sure what’s wrong. I’ll begin coaxing him downstairs using his food bowl today. If that doesn’t work, I don’t know what will!
Incidentally, I’ve begun giving him curcumin again. And he also gets a daily shot of cortisone (administered by yours truly). Other than that, nothing. Because the painkiller medication had turned him into a zombie, the vet and I decided to forget about it. I hope the curcumin will help lessen his pain, coupled with the cortisone. Anyway, he doesn’t seem in pain, and I know the signs by now…
But I digress! As usual… šŸ™‚
The MAIN reason I’m writing this post today is that I came across a very interesting CNN article. Well, well, it seems as though coffee drinkers are lowering their risk of dying.
Have a look: goo.gl/R9gEUT
Great bit of news for today, eh, for those of us who drink coffee!!!

Puzzola, 2001-2017

Stefano and I had Puzzola put to sleep this morning at the vet hospital. There was nothing more we or the vets could do…
We were with her almost until the end, until the vet told us to leave (the final stage can be hard to watch)…

So…my sweet girl is gone.


P.S. Even though Stefano took some photos of her yesterday, knowing they would be the last, I wanted to post a couple of photos I took of her in happier times…

This is how I will remember her:

1. I took the first photo in 2005. She really loved getting inside cardboard boxes, like most cats.

2. But hey, if you can’t fit inside the box (see above), no matter. You can squeeze part of your body inside, and leave the rest outside…Nobody will notice.
Year: 2013, the year she was diagnosed with hyperthyroidism.

3. And if there aren’t any boxes around, the little sink in the little bathroom will do nicely, too…Year: 2013.

4. Sitting at or on the table while we ate was also one of her favorite things. And if we were eating something that she could eat, too, I would let her lick my plate.

Ciao, amore mio…You gave us so much joy…

Kitty update

First of all, many many many thanks to everyone who’ve sent, and are still sending!, best wishes for my cats’ recovery…on the blog, via private email, AND on Facebook. I appreciate it so much!
They’re both home. Yes, yes, that’s great news, but we’re still not out of the woods, yet. In fact, far from it. Let’s start with Puzzola, our eldest.
I brought her home on Wednesday afternoon, after just one night spent in the vet hospital. Since she’s become so dreadfully skinny, the vets wanted to do a bunch of tests on her, and it was just easier to have them done there, especially the early morning tests. But, duuuh, she was NOT happy there, at all.
When I brought her home the following day, you could almost see the joy in her face. She leaped out of her carrier like a kitten, walked–a bit unsteadily but purposefully–into the kitchen right over to one of the water bowls, and then she proceeded to drink like a camel after a month in the desert. I know, I know that isn’t a good sign. But after all, tests show that she has a UTI, so I hope her high kidney numbers will go down once we’ve treated that. And the drinking might be caused by the UTI…
But before dinner she gave us a BIG scare. Huge. She began walking around like a drunk person, and it seemed that she couldn’t keep her head up, so at one point her head was hanging on one side, then on the other. That was freaky!
After of bit of that head flopping, she almost collapsed on our cotto floor and stayed there for a while, motionless. We watched her like a pair of hawks.
She finally got up and walked over to us, I’d say semi-normally. She has had a few episodes like that since she’s been home, but they aren’t as frequent and don’t last as long. The vet says it’s a neurological problem that might be connected to the fact that she didn’t really get any sleep in the hospital. Hope so. I haven’t seen her do any “flopping” today, although she does collapse on the floor and play dead once in a while. I think it’s her racing heartbeat (caused by the hyperthyroidism…which has gotten a bit worse).
Otherwise, she’s fine. She’s very loving and wants to be petted often. And she jumps on chairs to reach the dining room table, so her will to live is simply amazing.
One important point: I asked the vet is Puzzola were suffering, and she said no, she didn’t think so. She added that this condition will make her tired, but that’s it. Okay, good.
Moving on to Piccolo, well, when he came home on Thursday evening, to be honest I didn’t think he would live very much longer. His liver isn’t in great shape, and then we have the problem of his spinal column, which is the cause of all his pain (at least, that’s what the vets think). The painkiller they were administering at the hospital had turned him into little more than a vegetable. However, he was in NO PAIN on that painkiller (a derivative of morphine), so I suppose there IS a positive aspect to being a vegetable…
After I brought him home, he went and lay down in the cat litter box (see photo, which I just took…). He’s been in and out of that specific litter box, and I don’t understand why, really. Of course I’m keeping it SUPER CLEAN. Anyway…I hope he will leave the icky box once he begins recovering a bit more. To think that he has so many comfy cat beds on the bed in the guest room! And of course we’d be super thrilled if he slept with us! Oh well…
After he got home from the hospital, he didn’t eat for almost 24 hours. The vet told me to stop giving him the painkiller, to see if he’d start eating again. Note: I’m giving him a shot of cortisone every morning.
Anyway, yesterday evening, Stefano and I still couldn’t get him to eat anything and had to force-feed him, using a syringe (without the needle, of course!) full of watery wet food. That was really not fun…not for him, not for us.
On a positive note, today went much better. šŸ™‚
This morning he began eating on his own. I was close to tears, seriously close to tears…of joy, of course.
Now, I still have to take his food upstairs to him (he hasn’t been downstairs since I brought him home). Then I have to place the food right under his nose and coax him to eat it (sometimes using my finger…he will lick ANYTHING off my finger, normally), and this takes quite a while. No problem, I’m a very patient mom.
But hey, the good news is that he’s EATING ON HIS OWN…And drinking a bit of water, too, so I probably won’t have to give him an i.v. And I also don’t think we will have to force-feed him again. YAY!
I just don’t know what’s going to happen…Only time will tell.
One thing is clear, though: I will NOT let either cat suffer.
That’s what I would want for myself, too: NO SUFFERING.
But right now I really feel that I will be able to pull both of them out of this dark tunnel and back to their usual selves and routines.
Anyway, that’s the cat update…sorry it’s so loooong!!!
Take care, everyone!!! šŸ™‚

Puzzola and Piccolo in the vet hospital

Piccolo
This is a post about our two eldest cats: Puzzola, who is between 16 and 17 years old, and Piccolo, who turned 14 in April. They’re both in the vet hospital right now.
It’s a long story, but essentially they both started doing poorly about two weeks ago. Piccolo slowly began losing his phenomenal appetite and spending way too much time motionless on his cat bed (on the guest room bed).
I took him to the clinic as soon as I realized that something was very wrong. The vets found that he has a problem with his spinal column (I forget the name of this condition, but it has to do with calcifications of the vertebrae), which makes it very painful for him to move around, poor dear. Also, about five years ago, Piccolo had a terrible bout of pancreatitis that almost killed him, and we were told that he would always have issues in that area. Now, in fact, thanks to an ultrasound, the vets have spotted some sort of lesion on his pancreas and a nodule on his liver. His liver is also not doing very well. In short, he’s a bit of a mess…
And Puzzola, who has been suffering from hyperthyroidism since 2013, recently began eating less and less, no matter what delectable foods I cooked/offered to her.
Puzzola
This morning I decided to take her to the vet hospital, too.
She is now in a cage next to Piccolo, so at least our two kitties are together.
We’ll know more tomorrow, after more tests are done on both of them. Puzzola is going to have a heart ultrasound tomorrow morning, and Piccolo is going to have a biopsy of that lesion…Yikes.
Heartbreaking for us. Our cats mean the world to us, but all we can do now is wait and hope that they will both pull through and be well again.
Fingers crossed…!!!

Testing a new blog theme

Because of a recent problem with my blog, which has now been fixed, fingers crossed, I had to change my blog’s theme. I will be fooling around with a bunch of different themes in the next few days, weeks, centuries, but I’d appreciate your feedback. Thanks!

My current protocol

I have been getting quite a number of requests from blog readers wanting to know more or less the same things: how much curcumin I take, how I take it (with a fat, with cocoa, etc.)…and so on and so forth…

Instead of replying to each and every one of you, which would take heaps of time, I decided to write a quick post today about this issue.

Dosage: Every day I take 8 grams of C3 Complex curcumin = the curcumin that has been used in the MM, SMM, and MGUS clinical trials.

As for brands, I prefer Doctor’s Best, simply because of itsĀ easy-to-take one-gram tablets, which you can sometimes find at a relatively decent price if you shop around online a bit…

Note: I am actually running out of the D. Best curcumin and will soon have to buy some from a local Italian pharmacy. The Italian curcumin will simply be C3 Complex (it won’t have a brand name, that is). I mentioned that merely to point outĀ that for me the important thing is for my curcumin to be the C3 Complex, and that it come from a reliable source.

When I take it. I takeĀ TWO doses of curcumin a day: 4 grams around lunchtime, 4 grams around dinnertime. I simply swallow my tablets with a glass of water, usually. No fats, no quercetin (see below).

That’s the main part of my current protocol.

I alsoĀ take Nigella Sativa (black cumin) every day. I grate the black cumin seeds over my food, using a simple, non-electric grinder (such as a flax seed grinder).

I ran out of quercetin some time ago and haven’t yet found a reliable supplier here. So I am not taking quercetin…haven’t for ages, in fact. Nor am I taking fish oil. This means that I’ve cut down on my daily supplement intake. I mean, at one time I was taking more than 20 pills a day…I guess we all need a break sometime! šŸ˜‰Ā 

Current experiment: Ganoderma lucidum, or Reishi…the “mushroom of immortality.”

Remember the 2006 study titled “Ganoderma lucidum causes apoptosis in leukemia, lymphoma and multiple myeloma cells“? No? Well, if you are curious to learn more about it,Ā do a Search of my blog for “Reishi,” using the handy Search box on the upper right.

Just quickly, though…I began writing about G. lucidumĀ in July 2009. Because it sounded so promising, I decided to test it, but back then I didn’t buy enough extract for a proper test, at least that is what I remember. And I couldn’t get any more here in Italy. Well, things have changed. I recently found a reliable (at least, I hope!) G. lucidum product at my local pharmacy, and so here we go again, but this time I’ll have enough. I’ve beenĀ taking almost 2 grams a day, together with myĀ curcumin…which means I divide it into two one-gram-ish doses.

Of course, I don’t know what the outcome of thisĀ curcumin/G.lucidum combination will be.Ā I’ll let you know this fall, when I have more blood tests…

That said, I feel fine, absolutely fine…fit as a fiddle in fact…or rather, as fit as a fiddle can be in this horrendous Florentine heat! šŸ˜‰

Now, just to add a little bit of silly-ish news: my Fitbit, which Stefano gave to me as a present a few months ago, says that I am doing “excellent” (!) in my, er, age (!) group. Way toĀ go, eh!?! Yeah! (But hey, my AGE group? How dare they! šŸ˜‰ )

I think that’s about it…oh, but I’d really love any comments from you…For example, what do you take, and how/when/etc. do you take it? How has your protocol worked for you? I would love some updates, especially from those who haven’t been in touch with me lately. I wish I could keep track of everyone, but I get so many messages on a daily basis…so…it’s impossible. Anyway, I’d really appreciate it if you could find the time to drop me a line or to leave a comment on this post. Thanks a lot!

Take care, everyone, and…see you soon!!!Ā  šŸ™‚

Excellent videos offered by Myeloma UK

I just finished watching one of the, as my post’s title suggests, one of the excellent videos offered by Myeloma UK. This one was called “The effect of myeloma on the bone marrow.” Here’s the link: goo.gl/zfCU5n,

You will find many more animations on the Myeloma UK website, explaining, in easy-to-understand language, all sorts of things, fromĀ the origin of the Ā myeloma cell to the genetic causes of myeloma…Plus it has interviews with patients and also doctors on all sorts of topics, including fatigue caused by myeloma, travel issues, issues for younger patients…And much, much more.

Highly recommended website!

A Johns Hopkins researcher discovers a way that may slow down or even eliminate cancer metastasis

I just finished reading aĀ fascinating article about a very promising new discovery, which may be able to actually eliminate metastasis, that is, the spread of cancer from its primary site to new areas of the body.

And I quote: “Typically, cancer research and treatment has focused on shrinking the primary tumor through chemotherapy or other methods. But, the team said, by attacking the deadly process of metastasis, more patients could survive.” Aha. Interesting, very interesting…

The article is really easy to read, so, without further ado, here’sĀ the link:Ā goo.gl/ibM91B

By the way, the article mentions two pesky Interleukin proteins, IL-6 and IL-8, which are involved in myeloma, too…and NOT in a good way, either, as we should all know by now. But the good news is that curcumin inhibits both of these proteins. Good news, indeed…

Food for thought!!!

The scolding kingfisher

Months ago, weĀ wereĀ invited to London by good friends of ours (I met Paul via my blog years ago, and we have been friends ever since) to go seeĀ Trooping the Colour,Ā the official annual celebration of the Queen’s birthday carried out byĀ regiments of the British and Commonwealth armies. It is quite a spectacle…We’d seen it five years ago and enjoyed it very much, so we decided to go this year, too. Just for a weekend. Going to London is so easy: there are direct, cheap flights to Stansted from Pisa…

Anyway, that is where Stefano and I spent the first the first weekend in June.Ā Msargaret Kingfishers fighting 1230335

Last week Paul returned to Florence with us, and in fact he was here forĀ Stefano’s birthday (June 7th: TANTISSIMI AUGURI!!!). He spent a week with us, mostlyĀ photographingĀ the birds inĀ the Parco della Piana, one of Florence’s main nature reserves…Itā€™s a great place to photograph black-winged stilts during their breeding season, for instance, but you can also find night herons and sacred ibises there, and many other species, too, of course.

And then there are the kingfishers.Ā I absolutely adoreĀ kingfishersā€¦such beautiful colorsā€¦And fun to watch, too…

But try to get one in flight: for me, an impossible feat.

But let’s get to my story. Yesterday morning Paul and I wereĀ sitting inside one of the reserve’s hides, waiting for some bird activity (of which there wasnā€™t much for a long time), trying not to sweat too much (oooof, verrrrrry hot in Florence right now) or fall asleep…zzzzzz…

Our patience was rewarded at last: two kingfishers perched on a branch over one of the ponds started to becomeĀ extremely agitated. Based on our observations, this is what we think had been going on:

The adult had been diving and fishing over and over in the pond, in most cases successfully. But it was swallowing all the fish it was catching, so it looked like it was showing its “baby” how to fish. Well, okay, as you can see, the two birds were almost the same size. This was no “baby,” so from now on I will call it “Squawky.”

Even though SquawkyĀ was diving and really trying to catch a fish, it wasĀ coming up with nothing, and had to rest afterwards for quite some time, offering many photo opportunities to the two hot and tired photographers in the hide…But oh, how I feltĀ sorry for Squawky!!!

Then at one point the tired, terribly frustrated, and probably very hungry SquawkyĀ began fluttering its wings in front of its parent, beggingĀ to be fed. And that was our stroke of luck…the photos we’d been waiting for…

After a fewĀ seconds of all this annoying fluttering, the adult began severely scolding its offspring, screeching like a pterodactyl. Squawky didn’t actually seem very perturbed and kept fluttering, with its mouth wide open.

I managed to take this photo, which, okay, isn’t so great, but it will at least give you an idea of what weĀ saw (you can click on the photo to make it larger).

I will have to go back to the reserve some day soon to see howĀ Squawky is getting along…Paul, who returned to London this morning, will certainly want to know, too! šŸ™‚