Curcumin Keeps T-Cells Alive

Yesterday I came upon a recent study on curcumin and immune disorders. Published in the June 2007 edition of the “Journal of Biological Chemistry” (http://tinyurl.com/3yqzc6), it is titled Curcumin Prevents Tumor-induced T Cell Apoptosis through Stat-5a-mediated Bcl-2 Induction. Yes, I know, the second part of the title sounds nonsensical to non-scientific minds like mine. But when you read the abstract (and I am hoping to get my hands on the full text), it becomes clear that curcumin protects our T-cells. Indeed, this study shows that it restores T-cells from tumour-induced apoptosis: Administration of curcumin to tumor-bearing animals resulted in restoration of progenitor, effecter, and circulating T cells. In other words, curcumin can REVERSE the damage, or some of the damage at least, done to our T-cells by cancer. Now, isn’t that fantastic news? The study concludes: Thus, these results raise the possibility of inclusion of curcumin in successful therapeutic regimens against cancer. No kidding!

An article published in “Cancer Research” in January 2007 (http://tinyurl.com/2yng6z) also looks at curcumin and immunity. Concluding remarks: Thus, our results suggest that unlike many other anticancer agents, curcumin is not only devoid of immunosuppressive effects but also acts as immunorestorer in tumor-bearing host. I am all in favour of restoring my immune system!

Actually, this is not news to me, since a few months ago Prof. Aggarwal kindly sent me a study that he co-authored on this very topic (see my page on Curcumin and the Immune System). However, it is comforting to read a bit of updated research confirming curcumin’s strong pro-immune activities. This can only be good news for those of us who have compromised immune systems or autoimmune disorders.

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