What does curcumin have to do with transgenic fruit flies?

Last week I received a Google Alert that led me to this Science Daily article: http://goo.gl/G1M4b Excerpt: Five groups of diseased flies with different genetic manipulations were administered curcumin. They lived up to 75 % longer and maintained their mobility longer than the sick flies that did not receive the substance. The “disease” in question was an Alzheimer-like one, incidentally.

Well, I’m not a transgenic fruit fly, but even I can tell that I remember things now that I couldn’t possibly have remembered in the pre-curcumin period. And my mind is really sharp. Not that it wasn’t sharp before I started taking curcumin (hate to brag, of course… 😉 ), but now it could be used to cut sheets of stainless steel…Uhm, oh well, er, the fact that I “lost” my myeloma buddy, Honey, for about 36 hours doesn’t count. I mean, I found her again, didn’t I? 😉 (Some time ago, I must have tucked her inside one of the china cabinet drawers to keep her safe from my cats and then had simply neglected to put her back in her usual place. That’s all. Nothing to do with memory…or lack thereof…yeah, that’s it…)

Okayokayokay, quick change of subject! ;), I also wanted to post the link to an adorable video that I watched recently…nothing to do with myeloma, although some of you will recognize the place, which has a lot to do with myeloma: http://goo.gl/xEQsh Awwwww, sweet! The video reminded me of my parents who have been happily married for more than 57 years, still walk around hand in hand and are very active…(they also take about 4 grams of curcumin every day…)

Last but not least, here is another interesting link. Again, a Science Daily article, published last month, about the effect that diet can have on C-reactive protein: http://goo.gl/ixjzU In a few words, a group of healthy people on a low glycemic diet managed to reduce their C-reactive protein levels by about 22%. Twenty-two percent! Wow. That could be really important news for us, since CRP is one of the most important myeloma markers…There is a list of “low glycemic” foods at the end of the article.

Check it out! 


  1. Cool result. I did many years of post-doctoral research in fruitflies. What I can tell you is that the standard laboratory fruitfly, Drosophila melanogaster, does not have a blood-brain barrier –so whatever drugs you add to their food goes right to their brain.

    And yes: They have incredibly sophisicated brains that share, and time and time again have revealed, fundamental mechanisms conserved across all species, including CNS functions bearing on sleep, memory, addiction, alcoholism, and neurodegenerative diseases.

    So it is a GREAT and RELEVANT model system that can directly bear on human health and disease.

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