Punica granatum and myeloma

PubMed is such a fabulous treasure trove. A few days ago, I came upon a new, promising study on the devastating effects that extracts of the non-edible parts of a plant called Punica granatum had on U266 myeloma cells. The extracts not only stopped the myeloma cells from proliferating, but also took a hatchet to ’em, finishing them off for good: goo.gl/dYlXuK

Yes indeedie…Using more technical words, the extracts triggered apoptosis in this myeloma cell line…

Okay, and now it’s time for me to fess up…the joke’s on me! I mean, even though I studied Latin for many years, up to, and including, my last year in Italian high school, I didn’t recognize that Punica granatum meant pomegranate! Silly me!

And to think I’ve actually written FOUR medical-related posts on pomegranates (just search my blog for “pomegranate,” using the handy “Search” box on the upper right). Feeling a bit silly, now. Oh well, life goes on.  😎 

Anyway…Unfortunately, the anti-myeloma activity of this shrub/tree apparently isn’t in the fruit, but, as mentioned above, in extracts that came mainly from its stems and leaves, So the photo I took of two lovely pomegranates that we ate a few months ago is just for show, just to give some color to my post…
IMG_6596

The study concludes the following: “The data suggest that the extracts can be envisaged in cancer chemoprevention and call for further exploration into the potential application of these plant parts.”

Indeed!

The full study is NOT available for free online, so I haven’t gotten my hands on it…not yet, anyway. I’d love it if someone could send it to me…hint hint! Yes, that would be fantastic indeed…I’d really appreciate it. Thanks!  :-) 

3 thoughts on “Punica granatum and myeloma

  1. Charlotte

    Just found a few more articles about pomegranates:

    Anti Tumoral Properties of Punica granatum (Pomegranate) Seed Extract in Different Human Cancer Cells
    http://koreascience.or.kr/article/ArticleFullRecord.jsp?cn=POCPA9_2016_v17n3_1119

    Anti Tumoral Properties of Punica Granatum (Pomegranate) Peel Extract on Different Human Cancer Cells
    http://koreascience.or.kr/article/ArticleFullRecord.jsp?cn=POCPA9_2015_v16n14_5697

    Anti-inflammatory effects of pomegranate (Punica granatum L.) husk ellagitannins in Caco-2 cells, an in vitro model of human intestine
    http://pubs.rsc.org/en/Content/ArticleLanding/2012/FO/c2fo10258g#!divAbstract

    and co-authored by Dr Ephraim Lansky from Rimonest:

    Differentiation-Promoting Activity of Pomegranate (Punica granatum) Fruit Extracts in HL-60 Human Promyelocytic Leukemia Cells
    http://online.liebertpub.com/doi/abs/10.1089/109662004322984644

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