Curcumin: SIDE EFFECTS and WARNINGS

NOTE: for more recent posts, please scroll down. I have been taking eight grams of curcumin for almost 4 years (=in January 2010), and can report no harmful side effects. Quite the opposite. However, I have read or been told of a few side effects that are worth reporting. First, my experience.

In what I call the pre-curcumin era, I could barely climb the stairs in my house and was frequently tired for no apparent reason. I had fever-like aches in my legs, especially at night, recurrent night sweats and constant night-time PN (peripheral neuropathy). All of those symptoms have now almost or entirely disappeared. Another positive and unexpected side effect is that my (high!) cholesterol decreased by more than 50 mg/dL between January and September 2006. In the same period, my triglycerides went from 99 to 73 mg/dL.

Another thing that I had in the pre-curcumin era were chronic infections (yeast infections). I haven’t had ONE since I began taking curcumin. Such a relief!

Curcumin has also had a beneficial effect on my asthma. I have had asthma for years, and have never left my house without my Ventolin inhaler. At night, I had to take a couple of puffs on a cortisone inhaler, and sometimes a couple in the morning as well. I have now almost forgotten what my Ventolin inhaler looks like, and I take only one puff of cortisone (only as a precaution) before going to bed. This has been a huge change, clearly for the better, for me.

Warnings

My advice for those who are currently undergoing chemotherapy is to consult with their haematologists/oncologists before taking curcumin. I read that curcumin may lessen the anti-cancer efficacy of some chemo drugs, such as doxorubicin. In other cases, however, it may enhance this effect, as with dexamethasone (see the April 2004 Blood study). In any event, it’s best to be on the safe side. Check with your oncologist. When I began taking curcumin, I consulted my haematologist, and I wasn’t even doing chemotherapy.

People who have obstructed bile ducts or gallstones should not take curcumin, although curcumin prevents the formation of gallstones. I have also read warnings about people taking blood-thinning drugs such as coumadin. Curcumin is a blood thinner and should probably be avoided in that case (although Prof. Aggarwal told me that this was observed in vitro and in animals but NOT in humans). Some MM listserv subscribers have asked about my platelet count, and I can report that it has actually increased a bit in the curcumin era. So, hard to say. But again, best to be cautious.

If you have a stomach ulcer, you probably shouldn’t be taking curcumin. Ask your doctor, or write to Prof. Aggarwal.

A 2004 study published in Current Science tells us about the antifertility properties of curcumin: Curcumin also inhibits human sperm motility and has the potential for the development of a novel intravaginal contraceptive. So, if you are considering pregnancy, best to avoid curcumin. The paragraph in question is on page 5: http://tinyurl.com/2r2ubs

If you experience stomach rumblings after you take curcumin, eat a piece of bread (or two), or take it a half hour before you eat, or even with meals, if you really must. I can report that I did have some stomach rumblings when I tried mixing curcumin powder with flaxseed oil. All I had to do was eat a piece of bread, and they stopped. An easy solution to a minor problem. Should you have continuous trouble, though, do ask your doctor about it.

April 3 2007 update: a new curcumin-taker from one of the MM listservs wrote to tell me that he developed diarrhea after he began taking 8 grams of curcumin. He wrote to Prof. Aggarwal who informed him that diarrhea is a potential side effect for some. This is the first report I have had to that regard, but thought I should post it. My advice: if you experience diarrhea on a higher dose, cut back. And write to Prof. Aggarwal to see if there is anything you can do to solve the problem. I have second or third-hand information: an MD Anderson nurse told a listserv friend of mine to cut back on fiber intake to solve this problem. Yes, that might help.

May 30 2007 update: a good listserv friend reported breaking out in a nasty rash, and asked me if it could have been the curcumin she was taking (three grams). I looked it up online and was surprised to discover that rashes and hives are potential side effects of curcumin. She stopped taking curcumin, and the rash went away. She is going to try it again, though.

March 29 2013 update: If you are thinking about starting a family, you probably should NOT be taking curcumin. Check out the link in this post: http://margaret.healthblogs.org/2013/03/19/pap-test-result-and-and-better-than-a-condom-what-next/ 

218 thoughts on “Curcumin: SIDE EFFECTS and WARNINGS

  1. Lisa

    I just started curcumin today. Really tired of NSAIDS and shouldn’t be taking them as often as I am…also don’t want to go to a higher class of drug either. I was wondering if it helps with headaches and migraines as well as just swelling pain? So far it has helped some with muscle swelling, but not with nerve pain(Sciatica). Have you heard anything on Curcumin helping sciatica? Have you heard of dizziness/lightheadness as a reaction to curcumin?

    Reply
  2. Cher

    Hi margaret,

    I am really enjoying reading your blogs for I have learned a lot of things to know and to do regarding good and bad for MM.

    By the way I am an MM patient and in remission (Praise GOD). Just want to ask something, because I’ve read some of your blogs regarding the benefits of curcumin.

    I just started taking curcumin, its been a week now. Im taking one capsule a day. But I am still in Thalidomide 100mg a day. As per one of your blogs, thalidmode and curcumin is a great combination in killing the myeloma cells. Is my understanding correct?

    And also, how about taking green tea? I did not find any post by you regarding this. Is alright for us to take this?

    Anyway thanks to you margaret, your blogs really helps a lot! Contnue in sharing this kind of infos.

    GOD Bless always.

    che

    Reply
  3. Loriraine

    Can anyone tell me how young you can be to take curcumin? My daughter has been diagnosed with abnormal cells in her cervix and has just had a biopsy – her results won’t be through for 6 weeks, so if I can get her on curcumin now, hopefully, it may help in the depletion of the infected cell before her next visit which could be up to 12 weeks away. The problem is that between her having her 1st smear to her biopsy was 8 weeks and the diagnosis went from abnormal cells to advancing and all in such a short space of time.

    Any information would be appreciated.
    Thank you
    Lorraine (a very worried mommmy)

    Reply
  4. Margaret Post author

    Lisa: curcumin does have an anti-inflammatory effect, so it should help…theoretically, at least! I had a quick look online and found this study, too: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950845/pdf/AJHGv81p438.pdf
    As for dizziness, hmmm, no, I have never heard of that as a side effect. On the contrary, curcumin should help with that condition, too. Do you suffer from low blood pressure?

    Cher, some of my blog readers took curcumin and thalidomide or revlimid or velcade at the same time and reported beneficial effects. These are, of course, only anecdotal reports. As for green tea, I have an entire Page on EGCG (extracted from green tea)…look on the right of my homepage. Just one thing: if you are on Velcade, don’t drink any green tea on your Velcade day. Otherwise, it is fine (according to Dr. Durie).

    Lorraine, I don’t think there would be any problems, but perhaps you should check with Prof. Aggarwal (his e-mail address is readily available online, or you can ask me privately via my Contact form) at MD Anderson. He is THE world authority on curcumin. Fingers crossed!

    Reply
  5. Cher

    Hi Margaret,

    Thank you so much for the reply and I will read more of your blogs to gather more information.

    Thanks again & GOD Bless

    che

    Reply
    1. Katia Daniel

      Hi Margaret everything you said about curcumen is true for the past year withing 6 months apart my doctor run a blood test for me and was diagnosed with Lupus I cried so much then I said to myself I’m not going down without a fight since lupus runs highly in my family so I was scheduled to see a Rheumatologist I hanged there and did my own research so I strat using turmeric extract standardized from the brand Nature’s Way with 95% Curcuminoids within a month I went finally went to see the Rheumatoid doctor he did 3 blood test for me when result came back he told me I don’t have Lupus and my information rate went down from 49 to 36 although I have Fibromalagia he told me he is not going to put me any steroids and keep doing what I’m doing to bring the inflammation down to 20 I told him I’m taking turmeric and have osteoporosis too with arthritis truthfully I’m haven’t had no pain since I start this tablets I’m calcium (Alendronate Sodium and vitamin Do 50000 unites for osteoporosis and Savella as a muscle relaxer so my rheumatologist said I’m barely on any meds for my illnesses so continue doing what I’m doing and told to come back to see him in 2 months I mean wow I use to have so much pain tendinitis and pain all over my body that I had to ware a boot cast in other to walk now thank God I got no pain anywhere in my body except I’m tired from time to time especially after a long day on my feet though I don’t get enough sleep even though I’m using Melatonin but I’m so good and looking good thanks to you guys for putting herbal remedies online and now I need a doctor on herbalists or homeopathic anyone that can keep me away from big pharma sorry I don’t write proper English I didn’t go to far in school:(

      Reply
  6. Kellie

    We have a 7y/o with autism. He has numerous food allergies and occasional constipation (which always makes his mood and behaviors worse). We’ve been giving him curcumin in the form of Enhansa and have seen a wonderful improvement in his demeanor, his verbal ability, his level of alertness/awareness, and his overall cognitive state. He still clearly has autism, but any improvement in his cognition is a blessing!

    Reply
  7. Elke

    Just to let you know, I am another user of curcumin. At least Itried to be, but just 1000mg a day let to immediate diarreah.

    Reply
  8. Rudy Piltch

    Second paragraph below “Warnings” indicates “Curcumin is blood thinner, and should be avoided by people taking coumadin”. There is no warning on lable. My professional Health Care counselor has recommended 11 cap./day; the recommended dose on lable is 1 cap three times /day. I take 4mg coumadin /day. What’s your opinion regarding use and dose of Curamin?

    Reply
  9. Brenda L.N Diaz

    I have fibroids in my uterus, cyst in my uterus, ovaris,tubes and kidneys. Also I have irritable bowel syndrom. I just want to know how curcumin can help and how much I have to take a day to be save. I tank you in advance for any help you can provid to me.Thanks

    Reply
  10. Verna

    Hi there,

    I was diagnosed with breast cancer stage III last year. I was operated, went through chemo & radiation. I’m taking curcumin for several months now becoz i’ve read curcumin can kill cancer cells & can prevent recurrence. I’m taking 1 cap/day. My question is, how long can I take curcumin. Does it have an adverse effect with tamoxifen. Thanks, verna

    Reply
  11. Margaret Post author

    I have written to some of you privately but thought that a public reply might be of help to others, too. Thing is, my comment was rejected by my own blog anti-Spam program (!), so I lost all the URLs and don’t have time to look them up again.

    Therefore, I will just direct you to PubMed, which is the National Library of Medicine (great resource!). Go there and type search words such as “bowel curcumin” and “fibroid curcumin” and you (Brenda) will find a series of studies on these topics.

    As for dosage, since we are all different, the dose that works for me may not work for you. You will have to determine that on your own. I take 7 to 8 grams of curcumin (D Best and NSI, alternatively) every day. But you might be okay taking 5 or 6 grams. Impossible for me to say.

    Verna, do a google search for this title “Curcumin Modulates Tamoxifen Response in Resistant Breast Cancer Cells.”

    Before taking any supplements, of course, please ask your doctors first. Good luck!

    Reply
  12. mia

    TO LORRIANNE (worried mom)
    Lorrianne- I have had the abnormal paps two times and both times reversed it to normal paps with the following ( this was given to me as info from my gynocologist who is a lady open to more than just meds. She says this is a well known and quite effective thing to do when first detecting dysplasia.):
    Take each day:
    5- 10mg folic acid
    vitamin B6- 100mg
    beta carotene 200,000 i.u.
    vitamin C 100mg 3x a day
    zinc 30mg
    vitamin E 800i.u.

    I did this routine for several months. It worked! I was so worried. If you do it early, it can reverse. Then go to a regular one a day with folic acid in it. Good luck ( I believe you can look this up online too for more info)

    Good luck!

    Reply
  13. Loriraine

    Mia, thank you so much for your encouraging words and advice; and to all who have been in touch. I will pass these details on to my daughter and advise her to start a diary so I can pass on the outcome.

    Kindest regards

    Lorraine

    Reply
  14. Diane

    Do you know of anyone having hair loss from taking curcumin. A week after starting (3000mg/day)I started losing hair. I have lost half of my hair. I recently ran out and noticed a reduction.

    Would appreciate your thoughts.
    Thank you

    Reply
  15. Tacfarinas

    I am a 45 years old man. I started taking 95% curcumin extract one year ago (500mg twice a day) to control my thinning hair and hair loss. but I switched to taking regular turmeric instead for the main reason that the extract is exorbitantly expensive here in the UK and also because I reasoned that there must more to turmeric than curcumin and that they must work synergically. I take 2 heaped spoonfuls a day. If I must complain then the first side effect that comes to mind is the taste and after taste so I make sure I have orange juice at hand to wash it down. The other side effect is the smell of my urine witch is very strong and earthy if I may say so. Although I don’t like the smell I wont be stopping turmeric for a long time if ever. It keeps the hair on my head.

    Reply
  16. Larry

    Hello;
    My wife was diagnozed with bladder cancer and had a surgery last spring. She started taking curcumin 2 months ago. Her recent lab test showed lower hemoglobin. It dropped from 10 to 8 in 4 gm/dL months. I wonder if it is a side affect of curcumin.
    She first took doc’s best 4gm/day and has switched to meriva 500m twice /day + 1gm doctor’s best. Has anyone experienced this?

    Reply
    1. Mary

      I recently had my blood drawn and my Dr said my hemoglobin was high and couldn’t figure out why. The only thing I take is Curamin 3 capsules per day.

      Reply
  17. Margaret Post author

    Hi Larry, I have definitely not experienced anything like that. I went back in time to see how my own hemoglobin has behaved throughout the years…it still hovers around 13, which is what it was in the pre-curcumin period.
    However, curcumin is an iron chelator, so it is possible that it has affected your wife more strongly. If her hemoglobin doesn’t increase with her next tests, perhaps she should try going off curcumin for a month or so to see if it goes up again. Just a thought…

    Reply
    1. Linda

      request info on iron chelator?
      I have been takeing curcumin for one month , with less pain but am short of breath and tired.

      Reply
  18. Angela L

    Hello Margaret! I have Uterine Fibroids. I wanted to try Herbal Supplements that would slow the growth of my fibroids so the I could hopefully avoid having another Myomectomy. I have had two of them and hopefully I wont have anymore. Anyway, I went to Vitamin World last weekend, and the sale lady recommended to take 1000 mg of Turmeric Curcumin and 50 mcg of Selenium. I purchased the supplements but I have not yet taken them. I have discussed the with my Gyn Dr. and I am waiting on him to give me the ok. He is also doing some research on this supplement. I am nervous and a little scared to take this. Do you think 1000mg too much to start?

    Reply
  19. Leslie

    I have been taking 2 grams of curcuma with piperine for the last six months and after having repeated bouts of overactive bladder, I am beginning to wonder if the pepper could be the culprit. Has anyone had any negative reactions to too much pepper? Pepper is an irritant I would imagine. I will be very disappointed if I have to suspend my curcuma/piperine supplements- especially as I have just bought a large supply!

    Reply
    1. Diana

      Yes I also take Curcumin with Piperine. 5 grams per day and have been taking it for a year or so. Lately I have noticed that I have a burning feeling in the throat and upper chest area and can still feel the pills (even thought I have tried swallowing two cups of water) for a while after taking them. I have tried reducing the amount I take and yet I still get this feeling. I must say that I haven’t tried eating bread. I also have a large supply!!!!

      Reply
  20. Patti W

    Hi, Lorraine:
    I came across curcumin as a natural anti-canceral agent that induces apoptosis (cell death) in cancer cells. I have started on 2×500 mg capsules 2x per day.

    I have been vegetarian for over 30 years. I haven’t smoke or drank, yet I was diagnosed with adenocarcinoma of the stomach (stomach cancer). It could be because my father had it, though.

    Any other suggestions as to anything natural I could take would be appreciated.

    Patti

    Reply
  21. sarah

    Hi Margaret,

    My father is very ill with aggressive myeloma. He is 60 and they don’t give him long. However he has suprised them both twice in the last month when they told him he wouldn’t last night both times and he did!

    He has low platelets and low hemoglobin levels. Would curcumin be safe for him to try and if so how much?

    Do you know of anything out there that can increase platelet levels?

    Thanks for your time
    Kind regards,
    Sarah

    Reply
  22. michelle

    Hi, Margaret,

    Do you know if curcumin will help GIST (GI stromal tumor located in the Stomach)?

    Thanks for your time. I really like your blog.
    Kind regards.

    Reply
  23. A. Ingwall

    Hi Margaret.
    I was wondering if you have see nthis study: http://www.sciencenews.org/view/generic/id/71980/title/Worms_live_longer_with_thioflavin_T

    They gave Curcumin and Thioflavin T soo some wormes and it prolonged life on the worms alot. I have bought Curcumin because I came across this study…I have no illness but I sleep less and are more active since I started taken them(noticed effect after 4 days). Im 30 years old and in very good condition(well trained)
    My suggestion is that you try thinflavin T if you Curcumin helped alot on the conditions you have since they seem to be same type of substance. I have been unable too fund it though, soo if you would find it somewhere please let me know and send the link:)

    Maybe Thioflavin T can some other people here as well…
    Best Regards A. Ingwall

    Reply
  24. Nebbykoo

    I was diagnosed with MS in 2000.
    About 6 years ago, I started taking turmeric daily after researching anti-inflammatories on Google.
    The disease stopped progressing. I now take no drugs at all for MS. or anything else.
    It also stops nerve pain from MS better than NSAIDS or anything else I’ve tried.
    So I went from taking a drug that costs $3700/month, to a spice that costs around $8/lb. Basically, it helped me get my life back.

    Reply
    1. Liz

      Is there anywhere else I can find out more on this??? I’m really curious about the interaction of MS with your taking Turmeric.

      Reply
    2. Donna Kelley

      I was also diagnosed with MS Rheumetoid arthritis triennial neuralgia carpal tunnel hypothyroidism among alot of other things and found that taking doctors best Curcumin c3 500mg one time daily has helped me with all of my symptoms but seems to have made me develop diarrhea but that is ok if I can walk open doors cook and take care of my family. I am almost totally symptom free but wonder if I need to stop taking it or not. I read you should take it for two weeks but its hard not to take it because I have to use my extremities all the time. I have no other help so I hope it’s ok to take long term.

      Reply
  25. Beth

    I want to report my interesting side effect. Since I’ve been taking curcumin regularly (2007), I’ve had remarks from my dental hygienist about how plaque-free my teeth are. I’ve done nothing different in my tooth care regimen. I’m thinking that the curcumin had impeded the collection of plaque somehow. They hardly have to scrape anything off. It’s been great!

    Reply
  26. Deana

    I Do Not have cancer But my younger sis has Breast Cancer Twice (Was NOT Clean for 5years) Now she has Bone Cancer Does anyone think this may Help Her life!!!!

    Reply
  27. naz

    I have psoriatic arthritis for the last 15 years and have been treated with all possible medicine available now. I had to stop these medicine after 3-4 years because of their side effects. Rheumatologist has advised me to start anti TNF treatment which i am reluctent to use.

    I read that Curcumin is natural source of ant TNF drug, can i use this? where can i buy it does it has severe side effect…. CAN SOME ONE HELP ME Plaease.

    Reply
  28. A. Ingwall

    Hi, Naz
    I buy it from supplementspot.com use the code THM11 when you buy, then you get 10% off.
    Curcumins side effect is generally diarre. It’s a spice soo just as some people get a diarre from spicy food some get it from curcumin. Just decrease the amount of curcumin if you get that sideeffect until ur body gets used to it(the stomach that is)

    Don’t know if it works or not on psoriatic arthritis but you might as well try it, you got nothing to lose…

    Reply
  29. mary green

    Hello margaret, I too am a little scared of trying curcumin, have just bought a bottle…quite expensive, but worth it if it helps! I had a botched epidural years ago and had a chemical meningitis because of it and have had health problems ever since, so even though I look after myself I am always a little nervous about try ing something new! I have a hiatus hernia and sometimes get a bit of inflamation of tummy . will I be ok to use curcumin? Kind Regards, Mary Green

    Reply
  30. Gail

    Hi Margaret, My husband has been diagnosed with StageIV lung cancer and is completing his second round of chemo txs. They consisted of docetaxel and carboplatin. My question: is it safe for him to start curcumin now? I have read so many articles about the good things that curcumin does for cancer pts.

    Reply
  31. Frank

    Hi Margaret,

    I had my Gallbladder removed several years ago and I just had a Umbilical hernia repaired on May 13, 2011. Can I us Curcumin?

    Frank

    Reply
  32. Rod

    Hi Folks, I’m a Complementary therapist awaiting results of tests on a “lump” discovered recently; and just found this site. I hope the following info. is helpful to everyone as these are avenues I am following also.
    Allimax.ca (parent company in UK) a wide ranging treatment capsule
    Another is IP6 + inositol.
    Jason Vale and benefits from juicing/raw food etc.

    I sincerely hope this helps many of you and thanks go to you Margaret.
    Very best wishes to everyone and their families. Rod

    Reply
  33. Tom

    I started taking one Doctor’s Best Curcumin C³ Complex with BioPerine (1000 mg tablet) daily about two months ago. I’m a 65-year-old man and was told I would need surgery on my right knee and right wrist because of recurring pain. Since taking the curcumin the pain in both areas has completely disappeared and surgery is no longer needed. I feel healthier than I’ve felt in years and plan to continue taking curcumin. I’m also happy to report that I’ve had no noticeable side effects from the curcumin. I’ll be going for my yearly physical in November and am eagerly awaiting my cholesterol results to see if it has gone down.

    Reply
  34. mary green

    Dear Margaret, I asked a question about taking curcumin and hiatus hernia, but did not get a reply, appreciate you must be busy….do you have the e-mail address of the expert on curcumin ( sorry can’t remember the name of gentleman) kind regards, mary green

    Reply
  35. Jo Ann Stephens

    I am taking NSAIDS drugs for my arthritus. Can I take curcumin along with them or would it be best to discontinue the NSAIDS when taking this supplement.

    Reply
  36. Janet

    Well, my husband with pancreatic cancer is now in month 15 and our doctor JUST told us about Curcumin. Of course I have had him on it since the week he was diagnosed and also had found out it was NOT contraindicated with his chemo. He is doing well, last CT scan 3 weeks ago, clean, normal and tumor markers low normal. i believe in Curcumin!! My question for a friend also with Pancreatic cancer, is how do you know if Curcumin is contraindicated with a certain chemo? He is having Folfirinox and his doctor is not open to an alternative therapy and he is too intimidated to ask. I tried googling it for him but can’t find it. Does anyone know? Thanks Janet

    Reply
  37. Janet

    Thank you for this blog. I have shared it with a group on facebook all dealing with pancreatic cancer. You are helping so many people with this information!

    Reply
  38. peter

    Reversed 100 FAP polyps in my eldest son over 2 years with 2-3 grams a day – 60% reduction of size and numbers using Sabinsa.corp “curcumin C3 complex” ( sold as many brands names like Dr Best)
    Two other children with 60 and 100 polyps have been taking Curcumin at lower doses 1 gram and 1.5gram a day. From 1st to 2nd scope these doses have prevented polyp numbers increasing, but has not prevented one polyp increasingin size on 1.5 grams, and 16 polyps of the 60 increased in size on 1 gram a day..
    We can conclude 2 grams a day is the minimum effective dose in teenagers with 3grams a day is the safe recommended dose for colonic polyp reduction.

    Reply
  39. Terri

    I have been taking Doctor’s Best Curcumin C3 with Bioperine for 3 weeks. I started using 4 grams/day this week. This week I have started experiencing shortness of breath and a pulsing sensation in my ear. I have read that the shortness of breath could be an allergic reaction. I really want to keep taking the Curcumin, I have small bowel cancer that did not respond to chemotherapy. Should I stop taking Curcumin or go with a lower dose? Will the shortness of breath go away eventually? I’m having abdominal surgery in 2 1/2 weeks, I have read that I should stop taking curcumin 2 weeks before surgery because of bleeding risk. So I guess I’ll stop taking it for a while anyway. Any comments would be helpful.

    Reply
  40. Jodi Moe

    Are there any concerns using curcumin with a condition of lymphatic edema? I am hoping to control restless leg syndrome. Thank you

    Reply
    1. Jim

      I had restless legs and violent legs which would go straight up at a ninety degree angle while sleeping. I take 200mg of Magnesium at @9am & 8pm. My sister and granddaughter control their restless legs with Magnesium spray and a cream respectively, as needed.

      Reply
  41. Margaret Post author

    I’ve answered some of you privately…but I thought it would be useful to answer some queries here, too. Let me start by stating that I really know ONLY about myeloma. I am essentially a stranger to other types of cancer or ailments, so if you don’t hear from me, that’s probably the reason (in addition to my lack of free time…argh). Apologies!

    However, I might have a helpful hint. If you want to see if your particular ailment/cancer could possibly be helped by curcumin or anything else for that matter, have a look at PubMed, which is an amazingly useful resource: http://www.ncbi.nlm.nih.gov/pubmed/ Type your query (e.g. “hiatus hernia curcumin”) into the Search box, towards the top of the Page, and hit Enter. And you can also contact Prof. Aggarwal, whose e-mail address can be found online. Just look up one of the studies he has co-authored.

    Yes, 8 grams is 8000 mg, Richard. And yes, 450 mg, twice a day in my opinion, is verrrry little. That’s less than one gram. My parents and husband take almost 4 grams a day, which is 4000 mg, for preventive purposes.

    As for other types of chemo with curcumin, try checking PubMed, Janet. I didn’t find anything specific for Folfirinox, though. In that case, I’d write to Prof. Aggarwal…He might know about possible problems. So happy to read that your husband is doing well! :)

    Hope this helps! :)

    Reply
  42. Lisa

    Hi there. I came across your site while researching curcumin. I’m taking it for a benign brain tumor. I bought capsules made by Jarrow Formulas; Tumeric Concentrate Curcumin 95. Each capsule has 500 milligrams. Yesterday my acupuncturist told me that tumeric can’t work unless it is heated and taken with some kind of fat, like olive oil. How are you ingesting curcumin? Are you taking capsules or are you cooking with it? Do you know if there is there a tremendous difference in Curcumin and the tumeric used for cooking? Thanks so much for taking the time to reply.

    Reply
  43. JANET

    Hi. I’ve written on this site before.My husband, diagnosed with Pancreated cancer in 5/10 is still alive and almost in his 17th month after surgery, chemo and of course Curcumin..which I credit for him being in the 5% still alive after one year. Here is my question. I have given him 8 grams a day with bioperine and fish oil. Here is my question. Is it best to take the fish oil and bioperine a few minutes before the Curcumin? I also in addition, give him organic pepper fresh ground on a cracker about five minutes before. I want to do anything I can to increase the absorption. Our oncologist at Sloan finally is talking to her patients about Curcumin. I found out about it on this blog and I want to thank you once again as well as asking the above questions. Thanks..Janet. PS My husband just had a CT scan which was normal and all his tumor markers are LOW normal!

    Reply
  44. Ashok Lal

    I underwent right nephrectomy due to 5cm x4.5 cm x4 cm tumor which was diagnosed as lieomyosarcoma and had metastasized to RT lung. PET scan showed all areas clear except lungs. Two senior oncologists confirmed that the LMS will not respond to chemotherapy and nodules in lung are too small (largest being 14 mm) to risk radiation. Advised ‘wait and watch’ Prof. Aggarwal of MD Anderson suggested ‘CURCUMIN’ which I am taking for last one month. No negative side effect. On the flip side, blood sugar became consistantly normal. General condition has improved drastically, , bowel movement has become very normal, good appetite and and digestion. Awaiting next CT scan which due to in December. Eating veg.meals , feeling good. – lal

    Reply
  45. Andrew

    Dear Janet,

    It is so encouraging to read your husband’s experience with Curcumin.

    My wife has endometrioid ovarian cancer and the typical chemos have not worked for her. She is currently on a trial with a pi3k inhibitor (targeting pi3kinase mutatation and a mek inhibitor (targeting KRAS mutation)

    She is also getting treated at sloan kettering; and was keen to learn from your experiences. What chemo is your husband on and did your husband’s oncologist agree on him taking curcumin along with chemo? How much curcumin is he taking along with which chemo drugs?

    Margaret – I was keen to know from your experience / vast knowledge if combining curcumin with a pi3k inhibitor and mek inhibitor (targeted drugs) would be okay ?

    thanks a ton

    Andrew

    Reply
  46. Janet

    Hi Andrew – I totally believe Curcumin has made the difference. My husband was on Gencytobene and Oxyplatin (not contraindicated with Curcumin) He takes 8 grams per day, with fish oil, milk thistle, bioperine, vitamin c and resveretrol. We also did research on acid/alkaline theory that cancer and illness grow in an acid environment. We bought test strips and found we were both acidic. We simply bought apple cider vinegar and ate salads twice a day (just tomatoes and cucumbers) drenched in the apple cider vinegar and also started brushing our teeth with non aluminum bakind soda and within a week we were green on the test strip (alkaline!). Google it..makes sense to us. My question to Margaret is that there looks like there is a new Curcumin which is time released. Is that better? I picture the 8 grams going into my husband system and BAM hitting those cells..don’t know anything about the time release but if you think it is better we’ll buy is – they sell it as 1000mg with bioperine, I think its Ageless cures.
    Thanks –
    janet

    Reply
  47. Jo

    Hi,
    I’ve been diagnosed with Behcets syndrome which in turn has caused me to have fibro myalgia…I’m in constant pain but also have flare ups from time to time with my stomach..my joints are inflamed, ligaments, tendons an get a lot of ulcers in soft tissue..can any one please give me any help on whether Curcumin will help or at least not harm as I seem to throwing good money after bad on supplements and cure alls… I’ve just bought Collagen as this is supposed to help rebuild soft tissue..it has helped slightly but hasnt been passed by the food standard agency so I’m a bit concerned of any side effects.
    Thank you in anticipation.
    Jo

    Reply
  48. Pat

    Can anyone help me?
    Is curcumin safe to take with SSRI’s [especially paroxetine [for anxiety, depression] @ 40mg/day? I’m happy to cut down [slowly!] to 20mg/day, but I’m scared to go off paroxetine completely.
    Has anyone used curcumin AND a SSRI?, and what were the effects/side effects? I’ve searched the internet, and found very little regarding this.
    Also, if I [slowly] go off paroxetine, how long before I should start curcumin, and will the curcumin ‘kick in’ fairly quickly? Thank you. ?P

    Reply
  49. David

    Can you tell me please what the amount of curcumin there is in a tea spoon of tumeric powder, and is it ok to take this herb with my aspirin and blood presure tablets. I do also take anti acid tablets and have been taking tumeric powder for a few days now with no side affects, and there has been a great improvement in my arthritis pain.

    Many thanks David

    Reply
  50. Tom

    Hi Margaret, Hi Janet,

    I want to buy the Curcumin. However, I got confuse by the name like:
    Turmeric extract-raw, Curcumin standardize, Curcumin powder, or Curcumin Complex (Curcuma longa, rhizome standardized to 95% total curcuminoids).

    Which is that we should buy? Also, can you please help to know how many grams of raw fresh Turmeric is equal to 8 grams of curcumin standardized 95%?

    I thank you very much for the answers. My wife has liver cancer and a potential bone cancer and I hope you can explain a little bit more for me.

    Regards,
    Tom

    Reply
  51. Libby Rothwell

    Hi Tom

    The curucumin that Margaret takes is the C3 Complex Curcumin. If you look on her protocol it will explain it all to you there

    Reply
  52. Lana

    Does anyone know where to order nano curcumin?
    Apparently 60 x increased absorption- so 1 capsule is enough. MD Anderson studies are with nano- curcumin. There is a place in San Diego, that claims this technology, but they sell liquid, and all their products taste the same , little alcoholic, so I question that that products contain what they claim.

    Reply
  53. Faye

    This is the pill I am currently taking for fibromyalgia. I am starting to get some bruising and wonder if it is also thinning my already thin blood. Also, am I taking enough of this? Do you recommend a specific amount? I am feeling much better and have been taking it for 4 months now. Appreciate any advice you can offer. Thanks so much!
    faye
    Curcumin Complex (Curcuma longa, rhizome) (standardized to 95% total curcuminoids) Typical Profile: 875 mg *
    Curcumin (73–83%) *
    Demethoxy Curcumin (14–24%) *
    Bisdemethoxy Curcumin (2–4%) *
    Bioperine® Nature’s Thermonutrient® (Piper nigrum, fruit) (standardized to min 95% piperine) 5 mg

    Reply
  54. Jeff Crawford

    Hi Margaret, I did contact you some time ago regarding a ” threat” to start treatment for my myloma, which didn’t happen. Just to say I started taking C3 complex about 2 years ago, eight 1000mg tabs a day, reduced to four a day to regulate my over enthusiastic toileting. I am still hovering on the limit of treatment with little or no change in levels much to the suprise of both the hospital consultants and my GP. Some of my readings are worse than those of people who have reached treatment level. Why ? Is it the curcumin – I don’t know, but I am not stopping taking It !! I haven’t told the GP or consultant I am taking curcumin in case the tell me to stop. Do you think I should? Regards, Jeff

    Reply
  55. Rita Billson

    Hi Margaret,
    Thought you would be interested in an article published in the Seattle Times on Tuesday 11/1/2011 titled “Military Rations Take “Gourmet” Turn”. It covered the military food scientists located outside Boston, MA who are transforming the field rations called “Meal Ready to Eat” (MRE). A spokesman for the Center is where every item put into an MRE is tested and tasted. “Military technologists are lacing the MRE food with omega 3′s and CURCUMIN (which acts as anti-inflammatories)” was quoted. “Officials stated that the MRE has gone gourmet – or as gourmet as can be for food that has a shelf life of three years at 80 degrees and can withstand an airdrop from 1000′s of feet.” It appears that you were light years ahead of our Military regarding curcumin. Regards,
    Rita Billson, Fidalgo Island, WA, USA

    Reply
  56. Michael Creighton

    I have just completed second stem cell transplant. Now day 19 and feeling absolutely great. Wondering if it is wise to recommence my curcumin tablets at this stage or best to wait till we get the 90 day readings in which tell if the myeloma has gone into CR this time. First transplant we got protein readings down to 1 from 60 at diagnosis. any info about this?

    Reply
  57. Paula (New Zealand)

    Thanks Keith
    I am about to order the machine for making the Vit C as this is VITAL for low immunity, and prone to colds etc, I was just about to enquire if it possible to also do this for curcumin, and here you have answered the question. .

    Reply
  58. Teresa

    Can you tell me as well about GIST (Gastrointestinal Stromal Tumors) and if you’ve read or other reader’s know of Tumeric’s w/Curcumin benefits. Also, any data regarding PN, Autoimmune disease’s?

    Our Cat (Miles) has chronic Pancreatitis and I read on a Vets website that the dosage is 1/4 a humans because of Cats absorption rate. Do you or anyone you know use it to treat your animals? He has secondary diabetes because of Pancreatitis.

    Thank you for your Fantastic Blog!

    Reply
  59. Keith

    Paula

    Make sure that any Oz Ebay suppliers ACTUALLY export to NZ before ordering.

    Sometimes “free delivery” on Ebay just means in country of supplier!

    Reply
  60. Paula (New Zealand)

    Keith
    I was not going to buy on Ebay, but purchase a 2nd hand one from ‘Trade Me’ in New Zealand.

    Reply
  61. Roberta

    Did anyone answer Pat on the anti-anxiety and curcumin. I too am on but suffer from joint pain and have only recently seen the reports on curcumin. I would love to know more. I am 50 yrs old, overweight, taking effexor and have joint pain and swelling in my legs. Could this be an answer for me? I also take a calcium blocker for high blood pressure. Tired of taking 600 mg of Nsaids 3 times a day.

    Reply
  62. gabriel russo

    My Mayo Doctor recommended I take curcumin with bioperine. I consulted him about neuropathy. Is there any evidence or is anyone taking it for neuorpathy and if so, did it help.

    Reply
  63. Darlene Mellein

    Hi Roberta,
    I know about having anxiety, but I don’t know much about alleviating it. But I want to comment on taking the Nsaids, which I did too for sciatic and other pain. Turns out I have significant kidney damage, but not, they think, from my myeloma. We don’t know if it’s from the Nsaids, but they do have a bad effect on your kidneys, and I’ve been told to avoid them completely. Not what I wanted to hear. And not what I want to tell you, but just in case, you should check with your doctor, a nephrologist is best, about taking that much. Doesn’t it just floor you the number of things that are involved in and effect myeloma?

    Reply
  64. Paula L

    gabriel,
    I started taking curcumin, based on what I learned from Maragaret’s blog, to help stabilize paraprotein levels. Within a week, my neuropathy symptoms had all but disappeared. This was in late September…I only have the occasional twinge in my feet now instead of burning, pain and constant tingling electric jolts.

    Reply
  65. gabriel russo

    Paula:

    That is reassuring, however, I have not had any result yet. I hope I can get some meaningful result as you. I have been taking it a week or so. Thanks. Anyone else?

    Reply
  66. Ron

    Also just received some correspondence from Dr Aggarwal’s office that stated that curcumin with bioprene made no significant difference. I would appreciate any comments on this. The office also gave a supplier in Italy with a product with 50x bioavailability.

    Reply
  67. Janet

    Happy Holidays Everyone! I have learned so much from this site and want to thank everyone for their amazing information. My husband, who has pancreatic cancer, is starting month 20 with no evidence of disease. I attribute this to Curcumin. I am going to follow the links above with the machine (liposomol). I am still giving him 1100mg every morning with bioperine. I also saw that the doctor doesn’t feel bioperine doesn’t make a difference. This is hard to believe since I have spent many hours grinding fresh pepper over cream cheese for the fat and pepper combo. Aarrrgh!! If anyone is on facebook you can find me under Janet Shapiro Maday, please friend me. I’ve put a lot of the info I’ve learned on the Pancreatic cancer page. Invaluable info. Thanks again! Love, Janet

    Reply
  68. Janet

    Thanks Ron – still have three bottles of the Ageless Cures, but will definitely check out the product you suggested. Happy Holidays – take care…Janet

    Reply
  69. Ron

    Hi Janet

    I am not recommending this product, only seems that his lab made a point of referring to it for the bioavailability factor. Margaret would likely have some thoughts on this. I think their studies in the past used the C3 complex which is what I am taking, but had just started it.
    Looking forward to more discussion and opinions regarding this.
    There is also a sustained release form of meriva product available and I wonder if this would be advantageous

    Reply
  70. Mike

    Margaret, have you looked into this? Meriva seems to have been around and paired with curcumin for a while. Both Swanson’s and Vitacost offer supplements.

    The Meriva increase in bioavailability of curcumin may be better than the other way of adding Bioperine.

    I have a few questions about it though. Looks to me, they are combining different curcumin analogs than the C3 complex. But, will that be better in fighting MM? I remember Margaret mentioning that the BioCurcumin supplement she took did not work. I’m sure it was tested for bioavailability; but, was it the same as C3? Apparrently, more bioavailability was not what mattered.

    What would be the dose of Meriva? Margaret has said the 8g C3 for her may not be what is needed for others. And, how many times has she said, “less is more.”

    I don’t know what the dosage should be. I think taking any supplement should be in a monitored setting as Margaret is doing it with periodic lab tests to see how it is working. Even Curcumin.

    Here is a link that is interesting. Margaret, what do you think? 8g was mentioned as well as addding 20mg of piperine incresed bioavailability 2000 times. So would a lower dose of C3 with an added supplement of Bioperine be sufficient for good results? DNA damage doesn’t look good.
    http://toxsci.oxfordjournals.org/content/91/2/476.full?sid=6cf90a3a-98ef-4a68-ac5e-7404e27c8b40

    Reply
  71. Ron

    Mike

    Good points. Meriva seems to have a much higher concentration of curcuminoids in the trials at a much lower dosage. Thorne research offers a product of meriva in a sustained release form which would give a more stable level of curcuminoids at a less frequent dosage.

    Reply
  72. Margaret Post author

    Very interesting comments, everyone, thanks. This has turned into a sort of readers’ forum, which is fabulous! :-)
    Mike, I’m on holiday and don’t have time right now to read that DNA study, but I did contact Prof. Aggarwal yesterday about it, and he answered that chemo and radiation also cause DNA damage (and, I would imagine, much worse damage than anything curcumin could do, and probably at very low doses). I suppose that high doses of ANY substance might interfere with DNA, but that is pure speculation on my part, of course. Anyway, I have made a note of that study (which is fully available online, btw) and will have a closer look at it asap.
    In the meantime, if anyone (with a good head for numbers et similia) would like to try to figure out what the doses given to those cells would be in “human” dosage terms, please go right ahead! That would be a huge help. Thanks. :-)

    Reply
  73. Ron

    Margaret
    Enjoy your holiday. I am new to this site and you have put together an amazing site with much time and hard work.

    Ron

    Reply
  74. Eileen

    Mike,
    The study references Human Hepatoma G2 Cells which are liver cancer cells. So you WANT DNA and Mitochondrial damage to these cells by curcumin!

    Reply
  75. Mike

    Eileen

    What interested me in the study was their remarks in the discussion section that high doses of curcumin should be avoided and coingestion of piperine should be limited. To me, it appears their concern is broader than the HepG2 cells. To a lay person, These studies are a bit confusing. I thought the replacement of the piperine with Meriva may be a better choice if it has the same MM fighting abilities. And, that I do not know.

    Reply
  76. Zoe

    Hello,
    I just wanted to report some side effects i had from taking curcumin. I was taking it intermittently over a couple of weeks, and then i developed severe diarreha. My GI system was in distress. its a couple of days on now, and i am still having loose bowel actions, and when i do, it triggers off all the spasming again and i have to take meds to stop it. I have stopped taking it, but am worried about when the bowel which has now become irritated and overactive is going to settle down & get back to normal. :(

    Reply
  77. julia

    Hi,

    Fighting a battle with lung inflammation, horrible cough on top of my copd so after finishing prednazone the other day, i wanted to see if curcumin would clear out the garbage in my lungs. Tried it first time last night but had a very weird reaction – throat feels like it has spasms or something. Hard to explain. I’m positive it’s linked to the curcumin as i never get this otherwise. Is this a side effect and what’s going on with my throat ? I don’t want to stop the curcumin – i felt a noticeable improvement in lungs – very fast response. I tried this herbal 2 years ago – just 1 pill – and the same thing happened.

    Reply
  78. Ron

    Margaret, thanks for the response. I am currently taking 500 mg of Meriva in the form of Meriva-SR 250 mg twice a day. I am a mgus with a 1.2 m spike, and had spoken with Dr Aggarwal and he suggested starting with 500mg of the Meriva and upping dose as needed.
    You do a fantastic job with this blog and it is much appreciated

    Ron

    Reply
  79. Tanuno

    Ma’am margaret thanks for your blog, just want to ask, my wife has a history of cervical cancer and she BEAT THE CANCER!, but after 2 years dr. found a mass on her lungs and they’re advice for biopsy and ct scan for further evaluation, Is it good for my wife to take a curcumin capsules? and if good how much dosage she can take?

    Thank you and God Bless

    Reply
  80. Nataliya

    Hi Margaret,

    My mother was diagnosed with pancreatic cancer, stage 4, with metastasis in liver. 10 days ago her gallbladder was removed also. Wondering if curcumin could help in this situation. Would it be possible to get an email address of Professor B. Aggarwal? I have several questions to ask him.

    Thank you so much,

    Nataliya

    Reply
  81. Polka

    I’m taking chemo (Xeloda) and doctor recommended also curcumin. I was told to take 2 x day 2 pills of 750 mg each. I was taking it for over a month now but since 2 days I’m getting rush after taking it- I will lower the dose and consult the doctor on that during my next visit. I would also strongly recommend to all of you to check yourself for gluten intolerance. I believe that it is what gave me the colon cancer since I did not know I was gluten intolerant and was eating food containing gluten. Often gluten in our diet is the first silent problem. Best wishes to all.

    Reply
  82. LOis

    I have tried curcumin for pain and stiffness and the result was amazing – pain and stiffness disappeared almost immediately BUT it seemed to cause diarrhea. How can I continue to take this supplement without getting this side-effect??

    Reply
  83. Judith Jennings

    Is Meriva Gold a good brand of curcumin? Anyone out there used it? Is 500 mg. twice a day enough? I had ovarian cancer 3 years ago and don’t want it to come back. Please help! What brand is recomended?

    Reply
  84. Sheng Zeng

    Hi, Margaret,

    I am a 40-year-old man, and I was recently diagnosed with Kennedy’s Disease (a Motor Neuron Disease variant), which is no-cure as said by the western doctor. However some reports say taking curcumin may help. I am currently taking one pill (600mg) a day. After reading your article, I have concern about the antifertility properties of curcumin. I have never known this before. Could you please refer me to this article? The link http://tinyurl.com/2r2ubs is broken.

    Also I would like to know whether taking 1200mg curcumin per day is too much. My brother takes 1200mg and he wants a baby.

    I look forward to your help.

    Kind regards!

    Sheng Zeng

    Reply
  85. Mark

    Can anyone give advice on up set stomach caused by curcumin. It rally helps inflammation of the prostrate and I would hate to stop taking it. Would appreciate any advice. Thx.

    Reply
  86. Libby Rothwell

    Hi Mark
    Unfortunately in some people curcumin does cause and upset stomach. You may need to lower your dose and eat less fibre in your diet if you want to continue taking curcumin, its a tough one that, and is one of the side affects that they saw on the clinical trials.

    Reply
  87. Marc

    Did anyone research the effects of curcumin in a paste to be aplied on a specific area for inflamation? The benefits could be to have it concentrated over the needed part of the body instead of diluted all over. I have pain on some joints… great blog, tks a million!!!

    Reply
  88. brenda darling

    I have had chronic pain for the last two months, the doctors tell me that I have a virus in my muscles, and I must take a 9 anti-inflammatories a day, I went to my chiropractor and told him I can’t take those pills, so he mentioned Curamin. The first night I took one pill and did not wake from pain, but, because it was time to get up. After two days I am in the 50-75% pain free, range.

    Reply
  89. Dana Holmes

    Hello everyone, I have decided to increase my Dr’s Best c3 intake for the next round of labs in July (i am presently smoldering), plan to get to 8g per day. I also want to try adding Nigella Sativa. I want to try the supplement form…can anyone share their experience with the supplement? I don’t know how much to consume at a safe level. Thanks in advance to all who reply and have a wonderful day.

    Reply
  90. Libby Rothwell

    Hi Dana
    I take my Dr Best in the morning and evening before meals, 4g each time opened and mixed with yoghurt. With that I take 1g of Nigella Sativa Oil, then at lunch time I take a 500g tablet of Nigella but the seed this time in capsule form. I also cook with the seeds every evening, I buy 50g a week and mix them with 25g Cumin and 25g Coriander, this makes a nice mix and I add it it everything, the more spices the better. Will get my labs at the end of next month to see if this has made a difference. Good luck

    Reply
  91. Adam I

    Hope you know that the spice only contain 0,05% curcuminoids… soo no point in cocking with it if you want more curcuminoids. I take Revgenetics Sky curcumin. Costs alot more, but its micronized soo that’s why the cost is up.

    Reply
  92. Dana Holmes

    Hi Libby,
    Thanks so much for your reply. Is there a particular “brand” of the oil and capsule form you buy? I hope you see results at the end of the month. Please let us know !

    Reply
  93. Libby Rothwell

    Hi Dana
    I get mine from vitacost, it is called black seed, it comes in oil and powder, there are not many to choose from, i just took the one with the least additives in. The one is 9 dollars and the other about 14, so its not too expensive. Good luck

    Libby

    Reply
  94. pardi

    hi all,
    Just sharing what type of curcumin i take. Mine is known as Genus Serum solubilised curcumin which is sold in 15ml bottles. Its 100 percent curcuminoids without any additive. A friend of mine who has ovarian has consumed this GS for 2 weeks and said her body is providing positive answers. My spondolysis is also not giving problems since I consumed Genus Serum..

    Reply
  95. inge

    Pardi hi,
    Is this stuff you´re taking possible the same
    as they use in trial Margaret just wrote today?
    Where do you buy it from?
    inge

    Reply
  96. pardi

    Hi Inge,
    I am not sure of the brandname Margaret is referring but substance-wise sounds about the same. Best that u surf the Genus Serum website which on the bottle states genusserum.com. BTW, my brother who has osteoathritis tried this curcumin together with his prescribed glucosomine, celebrex and vitamins ACE, and discovered amazing results after a week.

    Pardi.

    Reply
  97. inge

    thanks to you Pardi, I´ll check the website.
    Interesting, isn´t it and today let´s go to the
    garden and pick some dandelions!
    inge

    Reply
  98. Linda

    Can you take curcumin if you are currently taking Tarceva for Lung Cancer? Also, after reading thru all of the info–I am confused as to what to buy and what to add to it, etc. Where can I find that info?
    Greatly appreciate any and all guidance.
    Thanks,
    Linda

    Reply
  99. keith

    Linda,

    One study using mice has found that curcumin increased tumour size for lung cancer. They surmised that it was not suitable for those with lung cancer who were smokers or ex-smokers.

    http://www.carcin.oxfordjournals.org/content/30/6/1016.short?rss=1

    Milk Thistle has been found to help kill LC cells.

    Keith

    http://www.sciencedaily.com/releases/2011/11/111115145236.htm

    It seems quite a few LC patients take milk thistle with Tarveca as well.

    http://www.iherb.com/Now-Foods-Silymarin-2x-300-mg-100-Vcaps/802

    You might also like to check out Inositol which is found in our food and is available as a dietary supplement. Its undergoing clinical trials at the moment for lung cancer by NCI and Mayo Clinic.

    Reply
  100. Ralph

    The dark side of curcumin

    Dear Margaret

    Most of the clinical studies are showing and stressing the beneficial properties of curcumin.

    This is an article from Spain (2010) which is focused on the potential negative effects of curcumin

    Burgos-Morón, E., Calderón-Montaño, J. M., Salvador, J., Robles, A. and López-Lázaro, M. (2010), The dark side of curcumin. Int. J. Cancer, 126: 1771–1775. doi: 10.1002/ijc.24967

    http://onlinelibrary.wiley.com/doi/10.1002/ijc.24967/pdf

    With the best wishes
    Ralph

    Reply
  101. Aimee

    Hi, it sounds like all the original symptoms were that of MSG or Glutamate consumption. I was just researching glutamate blockers and found Curcumin could help and was directed to this link.

    This could be worth investigating, as all these problems seem MSG related

    Reply
  102. alita

    since I start taking Curcumin drops 25-30 gtts. twice a day with meal I develop some irritation inside my mouth. I usually mix curcumin gtts. with 8ozs. of juice or tea. Is my dose ok.? Thanks,Alita

    Reply
  103. FrankH

    The warning about gall bladder issues should be taken seriously.

    I tried to start taking curcumin again about 6 months ago, but started having severe upper right abdominal pain which sent me to the emergency room. Ultrasound showed that my gall bladder was seriously enlarged due to ‘slush,’ and it had to be removed. The surgeon said it was one of the worst inflammations she had seen.

    I am certain that the curcumin triggered the problem, and I wish I had known beforehand that I had gall bladder issues.

    Reply
  104. John Williams

    On the bright side for curcumin I’d like to suggest that my 8grams a day has virtually banished my need for a hat to cover my bald head in sunshine. For thirty years I’ve been very susceptible to the sun burning me, even half an hour in the UK in summer giving me a very painful head and subsequent peeling. Now, after a year on curcumin, I go out and work in the garden in full sun without a care in the world. What other reason can there be?

    Reply
  105. Libby Rothwell

    Hi John
    I know that Vitamin D protects us internally from the sun, I guess it is quite possible that Curcumin does the same, I know that I feel so much better taking it and it seems to help with many symptons, Go Curcumin!!!!!

    Reply
  106. Rajvinder

    My father is suffering from 4th stage cancer in th lungs.He is undergoing chemo & has already completed three cycles.I was recommended curcumin ,by someone who has similar problem.
    But before i recommend this to him,I would like to communicate with Dr Aggarwal at MD Anderson.Can any one please provide me his mail ID,as the ones I have ,their is no response.

    Reply
  107. keith

    rajvinder

    Please check back to my reply of 2May to Linda who asked about Lung Cancer and Curcumin. One study showed it increased tumour size in LC patients. Milk Thistle appeared to kill off LC cells in lab tests.

    Reply
  108. William Oliver

    Hi Margaret, I was diagnosed with MGUS in Jan 2011. My IGG was 1700. Eight months later in Sep 2011 it had climbed to 2100. Then four months later in Jan 2012 it jumped to 2480. My hematologist told me it was accelerating and that by May or June it should have passed the 3000 mark, and we would then do a biopsy to see if my plasma cells were at or over 10%, meaning I had MM. Right after thet, I started taking Curcumin. I reached 6 grams a day, taken in 2 doses, each with a fish oil capsule ( Vtamin Shoppe Triple Strength Tumeric Extract 900mg with Bioperine 5mg). About a month ago I started taking 3 grams daily of Parsley Leaf split into 2 doses(Nature’s Way Parsely Leaf 450mg) and 3 gms of Dandelion Root split into 2 doses (Nature’s Way Deandelion Root 525mgs). I just went for another blood test, and my IGG was actually lower, at 2258mg/dl. My IGA is 64 and my IGM is 97. No real change on both of those. My Free Kappa light chain is 4.64mg/l and my Lambda is 5.95mg/dl. The KL ratio is .78. My regular doctor gave me the numbers, and I see my hematologist next week. These supplements have to be the cause for the decrease, as it seemed it was increasing more rapidly. The only problem I had with the Curcumin is some changes to my stool, which is an annoyance, but I can deal with it. I considered upping to 8 grams a day. Has anyone had any real problems at those levels? Thanks for your time and the valuable info, as this has to be the reason for my good news. Bill

    Reply
  109. Margaret Post author

    I’m so glad that your numbers have improved, William. I just wanted to point out that even if your plasma cells are > 10%, it doesn’t mean you have MM. That’s super important!
    If you have no CRAB symptoms, then most likely you have smoldering myeloma, which is what I have. And, if you’re smoldering, that means the following: NO TREATMENT (no chemo, that is).
    Anyway, good job! :-)

    Prof. Aggarwal’s e-mail is readily available online, so I can post it here, too: aggarwal@mdanderson.org

    Reply
  110. William Oliver

    Thanks Margaret. Actually, I made a typo. The sep-2011 IGG was 2001, not 2100. So the jump from then to Jan-2012 was even greater, showing a faster acceleration. The fact that the latest showed a drop is even more exciting, as I fully expected to be way over 3000. I am only hoping this last reading is not an aberation. Again, the only thing that changed were the supplements. I’m going to up my curcumin from 6 grams a day to 8. Hopefully I can tolerate it. This gets expensive, but a Hell of a lot better than the alternative. Thank you again. If I had never seen your blog, I never would have tried this. Bill

    Reply
  111. Faye

    Hi Margaret
    I too have smoldering myeloma but my levels are rising and I have recently tried taking Resveratrol 150mgs a day since I read it was good for MM but I have found it gives me leg cramps and weak upper arms,I was wondering if you have any experience of this supplement ?
    Many Thanks
    Faye

    Reply
  112. Beth

    Feeling kind of alone with MGUS here. Diagnosed 12 years ago and only went once to an onco. Bence Jones was fine. I never went back. I recently confided in new Dr. (GP) of my 12 year “secret” due to my fear (I completely freaked out!) Guess I just hoped it would “go away” since I had no symptoms. Dr. referred me to a hemo but have not picked up the phone yet (that fear!) So now that “monster” has been brought to light again by confessing to new Dr. IgM stays around 950-1000. I take Res and Curc and pray lots. Looking for what works to keep it at bay. Thank you all for being here and sharing. Sorry for long post!

    Reply
  113. Terri

    I have read through all the blogs and still did not see an answer concerning if you can take Curcumin if you have had your gallbladder removed. Does anyone know the answer to this?

    Reply
  114. FrankH

    Terri:

    If you’ve had to have your gall bladder removed I’d strongly advise not taking curcumin, as it could make the original problem worse.

    FrankH

    Reply
  115. FrankH

    My personal experience is that curcumin contributed to my gall bladder filling up with ‘sludge.’ Sludge and bile are generated in the liver, and will continue to be even if the gall bladder is removed.

    Reply
  116. penny edwards

    I have only taken Curcumin for a month for back and nerve pain. My problem is that I was just diagnosed with diverticulitis and was wondering if there is any connection to the curcumin.

    Reply
  117. Myrla

    I have had problem w/ bad sciatica& I had had accupuncture done before & take flaxseed,OPC 3,MSM,Glucosatrin,Type 1 11 & 3 collagen,befotiamine,bromelain,calcium citrate,vit d3,cinnamon,magnesium ,ubiquinol for so many years now due to my SLE. Every now & then,I get a setback but I bounced back easily. The sciatic pain had put me a very debilitating situation in Jan 2011 due to a respiratory problem as well as bad reflux from the hiatal hernia. Now,I started taking turmeric 2gms per day for 2 days & I can say how much difference do I feel now. Maybe this will help me to recover soon so I can take care of my sister in law in Canada who has terminal slow growing cancer,diabetes & neuralgia on the face. I have believed so much in holistic approach to my ailments.

    Reply
  118. Gloria Libman

    I have smm for 3 years. I am on no medication. I checked with my Dr at MD Anderson re curcumin and he has no opinion. Should I try curcumin or leave well enough alone. I am 83 years of age. I leave reading your material.

    Reply
  119. Ron

    Gloria,there are several docs at MD Anderson using curcumin in trials currently Fu Siqing Md is one. he is currently heading a study with Theracurmin. Curcumin certainly is worth a try as it also seems promising in Alzheimers and heart studies.

    Ron

    Reply
  120. Gloria Libman

    Margaret I have smoldering MM. Iasked my Dr at MD Anderson (Dr Wang) about curcurin and he had no opinion. I am not on any medication as yet and it has been 3 years. What do you think about me taking curcurin? Thanks

    Reply
  121. Jodi

    I find the comment on the rash interesting because I tried taking Tumeric liquid drops for fatigue and developed a hive-like rash. Is it possible that Tumeric is associated with sulfa? I have the same reaction to sulfa antibiotics. This is off the subject but may help someone. I tried taking glucosamine and chondroitin and had a horrible reaction…..severe nausea and vomiting after 7 days (a long-term reaction to sulfa). Some people get a rash right away with sulfa allergy and sometimes a reaction (like I had) develops once so much has built up in your system. Does anyone know if Curcumin has sulfa?

    Reply
  122. Richie

    I was diagnosed with SM about 2 months ago and immediately began a curcumin regimen after all the research I did and all the wonderful help from blogs like this. I built myself up to 8 grams a day taken all at once with 2 grams of fish oil for better absorption. Feeling pretty good but did notice that I’m starting to get excess gas and belching a lot. Not that big a deal but at times it feels like the gas buildup is causing pressure against my diaphragm and causing shallow breathing. I also saw that excess gas can place pressure against the vagus nerve and cause weird heart rates. I’ve noticed a bit of fatigue late afternoon mostly and wondering if it has anything to do with this? Anyone see any of these side effects as well?

    PS also beginning to add 2 grams quercetin and 200 mg apigenin taken together 12 hrs apart from the curcumin. Any comments about the total package?

    Reply
  123. John

    I recently consumed a few (maybe 6 or 7) Galaxy Minstrels (chocolate sweets) only to develop stomach and abdominal pain very shortly afterwards. This lasted for several hours. I know that I react badly in the same manner to Paprika Extract and Annato (both in the E160 category) so I had a look at the ingredient list on the packet. Apart from lecithin, there was only one other item, a colour that I did not recognise: curcumin.

    I’ve checked various allergy sources and it would appear that E100 (Curcumin) is not linked with ‘allergies’. Of course that presumably does not rule out intollerace which is technically different to allergy but can also be thoroughly unpleasant. I note from the above comments that some on here have had unexpected and undesirable recations including gall bladder problems, abdominal pain and bloating after consuming curcumin yet others seem to tollerate 2 or even 8 grams which is far more than would be found in the covering of a handful of chocolate candies.

    I’m a bit confused therefore, so can someone tell me a) curcumin cause allergic or intollerant reactions? or b) completely rule it out as a source of such reactions?

    Reply
  124. Cliff

    This has become a large forum and I have not read it entriely and so my question may already have been answered – please forgive me. I am currently taking warfarin, Ecotrin and Crestor for a clot which developed in my leg. I also have some small but painful sites of rheumatoid arthritis. The vascular specialist I consulted advised me against drugs like Celebrex to relieve inflamatory pain whilst on the above. Will curcumin, in combination with the above-mentioned medication, provide safe relief?

    Reply
  125. Savannah

    I have a question..
    I have recently read about the preventative effects Curcumin has for Alzheimer’s.I am a 34 year old women,
    My Grandfather had Alzheimer’s,and now my Mother has been diagnosed as well.
    I want to start taking something but am a little weary after reading this blog…
    Is this something I should try in smaller doses?

    Reply
  126. Adam I

    Define smaller doses?
    Most people only take 0,5 mg-1 mg a day, unless they do have a disease.
    Alzheimer people all have a really high level of Beta Amyloid in there brain, Beta Amyloid is a substance that gets created when a protein in your brain called APP breaks down, it breaks down in everyone. These particales are called Beta Amyloid and they are very sticky and form big clumbs together with each other. They form a “plaque” on the outside wall of the cell (only cells in the central nerve system) this plaque is removed by your immune system if you eat curcumin.
    Why is becuase the curcumin also get sticky with beta amyloid and when it does the immune system reacts and attack the beta amyloid, and therefore it gets dispelled from the body.
    You should start giving it to your mother, although she might need higher doses, but start with 1 mg for her. It’s important to take it with fat/meal since curcumin is not that easy to absorb for the body. But it is fat soulable soo empty stomach with water is completly useless…

    Reply
  127. Pete

    I think AdamI may may have the dose of curcumin a bit mixed up. I think he means a dose of 500mg (.5gms) to 1000mg (1gram) The most common capsule size by most manufacturers is 500mg. The FDA has determined it is safe to take up to 8-10 grams a day of curcumin. A preventative dose of two 500mg caps a day would be considered a low dose. However there are bioavailability ( product absorbtion) issues with curcumin so it is recomended to take some oil or fat at the same time,that maybe fish oil from the bottle, also a good source of omega 3 fatty acids or some have a little tub of yogurt because of its fat content. Research this website well as there is a vast amount of very helpfull info on it.

    Reply
  128. Adam I

    indeed I mean 0,5-1 gram,
    I have heard Omega-3 is not the kind of fat that curcumins needs, more like the generally bad fat. Like butter and icecream(pork)

    Reply
  129. Richie

    No Fred but I do think that some of my thinning spots are filling in, unless its just wishful thinking lol.

    I do think though that I may be one of the unluckys that are having stomach issues with it. I’ve noticed a tremendous amount of gas and bloating in my stomach and wondering if anyone else has come across this? I saw a few articles about the possible effect on the gallbladder but nothing really to narrow it down. I’m going to stop taking it for a while and see if it subsides.

    Reply
  130. J D

    For 2 years, my husband has had an oozing ulcer on the bottom of one of his feet. Would Curcumin be prudent since he does use aspirin theory & takes Carvedilol (Coreg®)?

    Reply
  131. Richie

    I wasn’t sure where to post this but I wanted to pass on some good news I received from my doc that hopefully will be encouraging for people.

    My story is recent diagnosis with SM about 4 months ago and at the time my initial labs were IGG of 2947 and an m spike of 1.9. All my other crab symptoms normal and not a single health issue, plasma was over 10% so he gave me SM instead of MGUS.

    I was fortunate enough to run into this site as part of all my research and immediately set myself up with a regimen. I worked myself up to the following over a two week period and have taken this daily ever since :

    morning

    8g C3 Complex
    2g Omega3

    evening

    2g Quercetin Complex
    200mg Apigenin
    8000 iu D3

    Went back for labs this last week or so and CRAB totally stable on all accounts but the shocking news was a dramatic drop in IGG to 2365 and mspike down to 1.7!!! Needless to say I was very happy and so was the doc (although he doesn’t attribute it to the supplements lol). I figured that’s what he would say so i took it in stride. Bottom line I feel great and he doesn’t want to see me for labs for another 6 months. I will stay on this regimen until then and see what i get. Stay tuned all.

    Richie

    Reply
  132. ZJ

    Hi. I’ve been reading “Margaret’s Corner.” I would like to know if I’m a candidate for Curcumin or at least a Turmeric supplement. I have plantar fasciitis and tarsal tunnel syndrome. I also have skin issues (atopic dermatitis) and muscle/joint pain. I DO NOT have a gall bladder as of 2002. If I am, I’m totally confused on what brand name / amount, what to take for absorption, etc. Thank you so much.

    Reply
  133. ZJ

    I apologize. I meant to add that I’m highly allergic to sulfa. I also take one low dose aspirin, one fish oil capsule, two calcium and two vitamin D pills daily. I was concerned about the blood thinning properties, since I take a low dose aspirin. Thank you again.

    Reply
  134. Ian d

    Hi, My 20 year old daughter had grade 3 (out of a possible 4) Endometriosis. She had to have surgery to remove as much as possible and still has some symptoms during her monthly cycle. Does anyone know if Curcumin could help to reduce her inflammation and if so what dosage? thanks

    Reply
  135. Marion Rebel

    Dear Margaret

    Hopefully you can help me with the following question
    using natural dietary supplements that are recommended
    on your site I try to slow down or even stop my kahler
    disease process.
    Is it possible that my endocrine system can get immune
    for these supplements when longer uesd?
    Is this a reason for a temporary stop or a variation in
    dosage?I look forwaed to hearing from you.

    Marion Rebel

    Reply
  136. Lola6

    Thank you for such helpful and informative advice on curcumin.

    I was reading the above post and someone posted about her daughter having abnormal cervical cells …..I was wondering if you could curcumin as a vaginal suposority? Or if you had skin cancer, would it not be beneficial to apply it topically? What about breast cancer? Could you not add some coconut oil and rub it into your breast/underarm? Yes, it would be messy, but I keep reading about stomach acids destroying its potency, so its not as active once it hits the bloodstream…..Any thoughts? :)

    Reply
  137. O.

    Hi Ian D., I just googled the problem of your daughter and found something very interesting (Curcumin arrests endometriosis by downregulation of matrix metalloproteinase-9 activity), have a look at http://www.ncbi.nlm.nih.gov/pubmed/19374255
    and, please, do a search on Google Scholar site with the keywords endometriosis + curcumin. Best luck!

    Reply
  138. Pietro P.

    Hello Margaret,
    your blog was indicated to me by Carole G. I am now 64 and I was diagnosed with MGUS type IgM on March 2008.
    I would like to contact you directly by email to share some experimentation i did and some ideas.
    Can I write in italian? It would be easier for me …
    I hope to hearing from you soon
    Thank you
    Pietro

    Reply
  139. Neha

    Hi Margaret, im having cold skin allergy and im suffering from inflamation so may i use curcumin? If yes in what amount of dose i have to use?

    Reply
  140. Sandra

    I take Tumeric powder 2-5% curcumin With Moringa leaf is it best to get curcumin by it self or is it the same as the tumeric and how much of each should I take a day of the tumeric power? or take it in a pill? I have Gere disease and hight blood, Hep-c auto-immune, a degenitive spine and tumors. I also take medical cinnamon.I get a lot of smelly gas. I seam to stay dizzy and mental confusion was also why I started to take it these nutritives.

    Reply
  141. ROZ

    WHAT A WEALTH OF INFORMATION. just been told that my uterus has cancer cells. Waiting on result of ctscan. Started Jarrows curcurmin one week ago. 500mg per day. Dont want to go on chemo. It is comforting to read all these blog. Will update on my results

    Reply
  142. Sheri

    Hi. My husband has Myeloma .He already had a stemcell trans. In 2008. His numbers are going up and some of the drugs that worked before aren’t now. They want to try him on a new chemo and we want to add this. But don’t want it to make it worse. We did some other natural thing and think it might have messed. Him up. His lightchains tripled in 2 months. What dose do u think would be good for him? Should we get the kind with black pepper? Getting really nervous. Please email asap. He is young and we have young kids. Thanks so much.!

    Reply
  143. Robin

    Hi – I need the email address for Prof. Aggarwal. I am taking curcumin for multiple sclerosis 800 mg a day and I am having a lot of abdominal pain even thought it is helping with my ms spasticity. I am concerned about internal bleeding. Thanks, R

    Reply
  144. Don

    Horrible allergic reaction to curcumin. I started taking curcumin July 2012 and after 1 wk started noticing what appeared to be mosquito bites on my ankles. However, after 3 wks these turned into itchy, painful blisters so I discontinued use of curcumin. as time passed the blisters moved from my ankles to lower legs, progessed to both forearms and to the back of my right hand. As of Jan 2013 I am STILL having problems. Been to the dermatologist; taken 3 rounds of anti-biotics; had 3 shots of Kenalog (cortisone); taken 1 round of Prednisone and 1 round of methyl-Prednisone; used Tea Tree Oil – NOTHING HELPS! – I look like I have Leprosy and must wear long pants and long sleeved shirts to work. The fabric on my shirt sleeves irritates the sores and I have pain daily. HAS ANYONE HAD A SIMILAR REACTION? CAN ANYONE MAKE SUGGESTIONS THAT MIGHT HELP MY SITUATION?

    Reply
  145. Adam I

    but U did use cortisone gel during this whole time right?(thin layer)
    Because shots of cortisone and antibiotics aren’t that specific. U will be treating the whole body with that.

    Reply
  146. Dimitra

    Hello- could you please tell me the e-mail address of Dr. Aggarwal? I have a question I need to ask… Thank you very much!

    Reply
  147. Ed

    I had Back surgery on Nov 5th,2012 and I have been in more pain than anyone could of expected my pain level from 1-10 is a 25 I cry everyday because I hurt so bad.
    it ranges anywhere from my left side of my stomach to shooting and constant pain in my legs. the Doctors sent me to a pain clinic just to find out there is only 2 things that might help, a spinal stimulator or putting a resovor in side of me with morphine inside of it. not to thrilled with either option.. a friend of my wife suggested that I take 3( Turmeric Curcumin) Turmeric ( Curcuma longa) (Root) 450mg and Turmeric Extract 50 mg 500mg and a vitamin called Alive have you ever herd of this?

    Reply
  148. Lynne

    Hello. Have been so blessed after finding this page while searching for a solution for my condition. I have diabetic (Type 1) gastroparesis and was put on domperidone to help with the nausea and to help the stomach empty and bowels to move properly. However, long term large doses of domperidone affect the pituitary gland and cause increased production of the hormone prolactin. One of many unpleasant side effects is hair loss. I am a 51 year old female so not happy at all about this. I have ground turmeric in my pantry but have never used it. It has passed its expiry date so will have to replace it! With a limited income as not able to work, taking the spice is the best alternative at the moment. How much should I take of the powder initially please? I have reduced the domperidone to lower the side effects but my bowels are no longer working properly and the hair continues to both recede at the temples and fall out all over. I am considering going on a completely liquid diet in order to stop taking the domperidone as the side effects have affected my quality of life and the “benefits” are cancelled out. Any suggestions are most welcome. Thank you.

    Reply
  149. Kayla

    I have been reading through a lot of these stories and can’t seem to find an answer to my question, which is: Is vaginal bleeding a side effect for anyone else? I started taking Curcumin 500mg twice a day in April. The effects were immediate in that my constantly aching knees, ankle, and hip became nothing more than tense with the first pill I took! But within two days, I started lightly bleeding. I thought nothing of it, it was about that time of the month, but it just didn’t stop. The curcumin certainly made my cycle easier but it continued on for 19 days, until I quit taking the curcumin. I’ve tried Curamin, which doesn’t cause that problem, but it also doesn’t work as well. My legs are bothering me again, so I went back to the curcumin and, just like last time, I started spotting within 2 days. Any advise would be greatly appreciated. Thank you.

    Reply
  150. Diane Seymour

    I have been reading your blog on curcumin which the nurse practioner on my Mayo team recommended to me, a SMM patient. I purchased Viramin World Double Strength Plus Bioperine Tumeric Curcumin 1000 mg. with 100 mg of Tumeric extract standardized to contain95% curcuminoids. I was wondering before I start if I am on the right track with this brand or should I seek out Doctors Best? I have been reading on Curcumin and find myself confused. Thank you.

    Reply
  151. Akbar

    Hi,

    My dad is suffering from Congestive Heart Failure due to Cardiomyopathy and Heart Valve Leakage. Due to this his liver has also become cirrhotic and his kidneys have been affected as well. Creatinine in the range if 1.8 to 2.8. Total Billirubin is around 3. Uric acid is high as well.

    Would Curcumin help? Please note that his BP is 80/60 almost all the time. His ejection fraction is 25%.

    Looking forward to your expert advice.

    Reply
  152. Tom

    Dear Margaret,

    I would like to ask you if Turmeric is safe for washing teeth on the long term. I have used it twice already and it had fascinating even after the first us!
    Is there something in it that could be detrimental to the enamel?

    Thank you for your answer!

    Reply
  153. Jo-Anne M Cole

    Margaret, I am so pleased to have found you via Facebook. I was diagnosed back in March 2013 with SMM and would have launched into immediate treatment had I not listened to my daughter, who is a nurse, and my GP. Both insisted I should get a second opinion and thankfully I did as I have no CRAB symptoms and will now be doing ‘watchful waiting’.
    I have found your articles on curcumin extremely interesting and positive and I would like to start taking it but I have two questions that perhaps you could help me with. The first is which brands carried here in Vancouver, Canada are recommended as safe. We just had a big expose on supplements being tainted with everything from pesticides to e-coli!
    My second concern is a gallbladder issue. I had mine removed in 2004 and it was a very nasty operation as I had been left far too long. I’m wondering if not having a gallbladder, which comes with it’s own set of issues, could make taking curcumin a problem. Perhaps you have read or heard something about this and could pass the information on.
    Thank you so much for any advice you can give. Take care and thank you again for your great web site!

    Reply
  154. dawn watts

    I am currently being treated at the Royal Marsden Sutton, UK under Professor Gareth Morgan. Currently on Pomalidomide, PredMeth and Cyclophos (as aspirin)

    Over the years (and more so recently) i’ve noticed there’s been a lot of hype/discussions about the benefits of taking Curcumin supplement / Turmuric as an aniti-cancer drug.

    I have taken the supplement many years ago when I first stubbled upon Margerets blog!

    Well I was keen to re-introduce Curcumin supplement into my diet. So I thought i’d double check with the Marsden, Sutton, UK.

    I thought I would share the feedback with you – I was particulary shocked to read that “High doses of antioxidants are not recommended whilst a patient is on chemotherapy as they may stop the chemotherapy from working so well” ! this was news to me!

    Have you been given similar advice?

    Feedback from Marsden
    · Preliminary research suggests that curcumin might have antioxidant and immunostimulatory effects.(1)

    · High doses of antioxidants are not recommended whilst a patient is on chemotherapy as they may stop the chemotherapy from working so well.(2)

    · Curcumin has antiplatelet properties, therefore in may not be appropriate if the patient has a low platelet count and is taking aspirin.(1)

    · One database stated that dietary turmeric (curcumin) inhibits cyclophosphamide- induced tumour regression in animal studies.(3)

    · Not recommended that a patient takes a curcumin supplement whilst on chemotherapy.

    References.

    1. Natural Medicines Comprehensive Database accessed via http://www.naturaldatabase.com [accessed 25.7.13]

    2. RMH Patient Information Leaflet – Vitamin and mineral dietary supplements (available via the intranet)

    3. Memorial Sloan Kettering – About Herbs accessed via http://www.mskcc.org/mskcc/html/11570.cfm [accessed 25.7.13]

    Reply
  155. Adam I

    A co worker that had tumour in her breast got curcumin from her doctor… so seems not to be a problem more on the opposite side of things it’s good to take. This was in Norway

    Reply
  156. Len Walde

    I have been experimenting with curcumin C3 Reduct for topical application, with some interesting results. The problem is I cannot find any over 100 mg. I have been suspending seven capsules in peanut oil.

    Sabinsa suggests 400 mg for oral use but can not find a source. Any help out there?

    Regards to all!

    Reply
  157. Adam I

    Hi, Len Walde.
    There is one skin Cream that I use that contains curcumin. There is also curcumin that is Micronized, Micronized means that one have used microwaves in the production to shake the molecule lose from each other. So the bioavailablity increases(the body takes it up easier). But since u are using it on ur skin I Think u definately should use some micronized curcumin for that since the skin doesn’t let much through is… sky curcumin is one brand u could buy which is micronized. Good luck.

    Reply
  158. Art

    Curcumin was recommended (verbally) by one of the most famous oncologists in Israel for my dad’ pancreatic cancer stage 4.
    Started from 1 gr daily, increased by 1 gr/d every next week up to 8 gr/d

    Reply
  159. AVe

    Hello, I currently started taking kyolic curcumin because I have fibrous dysplasia in my skull. They reduced the bone on my frontal bone and my left sphenoid. But they don’t know if its going to grow or not.
    My doctor gave me Anti-inflammatory medicine so the bone doesnt grow anymore, the medicines side effects are too harsh so I hope that this natural supplement works!
    Thank You.(LV,NV)

    Reply
  160. Maggie

    I’m curious if we can further find other means to a permanent cure with curcumin, My husband was diagnosed at age 45 years old a 1 year ago with a brain tumor later determined it was cancer call analplastic astrocytoma grade 3, he had no symptoms until he had 5 seizures and was rushed to the hospital and told at the ER that they had found a mass in his brain in the right thalamus, he was weak but was able to function normally, we weren’t told of the potential risk and under went a routine biopsy surgery a few days later, routine test of several blood analysis, 1 MRI and 3 spinal tabs the results of the spin were negative but the biopsy wasn’t, devastated and shock of the bad news we didn’t let it bring us down, we are still fighting towards the cure, and the good news my husband brain cancer has decreased dramatically we believe there is hope despite the bad headaches, between diarrhea, and constipation, sinus infections and blood clogs,induced diabetes and all the health issues due to the harsh treatments my husband remains strong and doctors are very surprise to see his remarkable improvement which he has made so we are grateful to see this tumor completely disappear we can never loss hope and faith.

    Reply
  161. Carole

    Margaret, do you or anyone else know if it is safe to take curcumin with anti depressants (SSRI). I believe that curcumin is considered a MAO-A/MAO-B inhibitor. I have been having trouble with anxiety since my diagnosis of Smoldering Multiple Myeloma. Any other suggestions would be greatly appreciated.

    Reply
  162. Carina Rascher

    I have been suffering for over four decades under a rare illness called Dercum’s Disease. The most prominent symptoms are lipoma in all sizes spread over and in the entire body, massive weight gain and severe pain. (Dercums is considered the second most painful illness there is) These deposits are caused by an ill functioning lymph system. What benefits would I have from taking curcumin? Should I then eliminate the two blood pressure medications I am presently taking? Otherwise I am on three different pain killers. I would very much appreciate any suggestions.
    For those of you interested in knowing more about, please look under http://www.lipomadoc.org
    Thank you and cheers,

    Reply
  163. CC

    This is a 2012 study I found interesting Curcumin Blocks Small Cell Lung Cancer Cells Migration, Invasion, Angiogenesis, Cell Cycle and Neoplasia http://www.plosone.org/article/info:doi/10.1371/journal.pone.0037960#s2 My Mom has lung cancer and it has shifted into her brain so I’m thinking about trying her on the Curcumin, her lung cancer is stable its the brain cancer we are worried about. One responder gave the link to a study where the Curcumin increased lung cancer tumors, however more studies have been done showing a decrease in size instead.

    Reply
  164. Dan

    HI Margaret, I started my mother on curcumin last week. she suffered a stroke in 2005 resulting in Vascular Dementia along with Alzheimers and Diabetes. I was her caregiver until last July when she fractured her hip and pelvis again.
    Unfortunately, I had to place her and she continued to deteriorate at an alarming rate.
    Since starting her on the curcumin she has started to regain her memory and personality. All of the staff are quite impressed and are surprised to see the real person.
    The day I started her I could see improvement within an hour and the next day I was a little worried because she was almost speaking in tongues with the memories rushing back in parts without any timeline, I wondered if I had made a terrible mistake and had made things worse.
    Lo and behold the next day, when I went for my daily visit the first thing she said was to ask me if I had eaten? This was the first time she had asked me about myself since she first got sick, I was almost in tears I was so happy.
    I have increased her dosage to 2 pills a day, one w/ breakfast and the other with supper, a total 850 mg of Clef des Champs Curcuma. When I see her doctor next time I will add another at lunch. I have tried to spread the word but people are reluctant, I only wish I could give it to the other residents, I know it would help them as it has my mother,
    On the other hand I personally had an episode in which I suffered a mini stroke 2 months ago and was in really rough shape. I was deteriorating rapidly, to the point I couldn’t rememeber what I went into the room for. I was lightheaded, dizzy, blurred vision and my front left lobe was throbbing. I went to the emerg. for an EKG and C-scan but both were negative although I went home I continued to get worse.
    I took 2 curcumin and that night I literally could feel tingling in my front lobe, I have continued to take a pill a day and was feeling quite well until yesterday when I took 2 pills at supper to alieviate some constipation but instead of having a BM I filled the toilet with blood, today I am trying to fill a 24 hour urine collection to check my kidneys because I have A systematic proteinuria, I was hoping after what I had read that the curcumin would help my kideys but instead I am unable to urinate more than an ounce or so at a time and in eleven hours have only discharged less than a cup. If I am not better tomorrow, then back to emerge.
    PS my mother has experienced no side effects and I am very grateful to you Margaret for your blog. I wish I could climb to the top of a mountain and shout out to anyone with a family member afflicted with the devastating Alzheimers about curcumin the miracle drug.
    All the best to you and god bless.
    Dan in Montreal

    Reply
  165. Camille Rajkumar

    have you ever had patients who have dementia show any slowing down or decreased in the disease that normally comes with this issue. Also if you do have gallstones what effect can taking Curcumin have on your biliary system or gastrointestinal system?

    Reply
  166. Chris

    I have been taking Curcumin for a few years now and it has really improved my health, we barely ever get any colds or flu anymore and my joint pain and stiffness is pretty much gone. I feel much healthier and look younger than before I started taking it, a very substantial good side-effect of its daily usage is greatly improved mental clarity and being generally less “foggy” in my head. Something great is going on with this stuff, whatever it is I am going to keep taking it twice a day. I’ve always used the Life Extension brand with the BCM-95 Curcumin extract, it’s only like $20/bottle through the link at http://www.CurcuminPills.com I used to buy it locally but now it’s over $30/bottle at Vitamin Shoppe so we definitely save a lot buying online and they ship free too. I recommend taking it with food always and just make it part of your regular routine, it is very well tolerated by almost everyone and I have not had any adverse effects after taking it for over 3 years now. I love Curcumin, honestly I don’t know how I ever survived without it previously! :)

    Reply
  167. Diana

    I suffer from osteo arthritis which is heightening as I get older. I am 67 years old. I cannot take anti inflammatory drugs due to stomach ulcers many years ago, and thought this natural product for pain relief may be my saviour. I am taking CURAMIN which contains curcumin, boswellia, DLPA and Nattokinase. I have read on the net that people who take a blood thinner should not take curcumin – I take Clopidogrel daily. I also take fish oil and Krill oil which thin the blood as well) Do you think it would be dangerous to take CURAMIN. Would it be beneficial to talk to a naturopath or a GP. Thanks in anticipation.

    Reply
  168. chris

    I really appreciate your blog. Thank you.
    I have a few questions:
    1)where do you have a summary of your complete program of black pepper, etc. with Curcumin.

    2)I have started Natural Factors’ CurcuminRich 300mg Theracumind, which is supposed to increase absorption through nanotechnology. Is this new super absorption form what is spoken of in the blog at 8000 mg per day? That’s a lot of pills. Is anything better or is this good?

    3) What is to be taken with it or what protocol to enhance it?

    4) Was interested to find that Drugs.com’s interactivity checker does not even know what curcumin is. Should I insert it in that program some other way to run their check with my other meds?

    Thank you for your promptest reply.

    Reply
  169. Irene

    Hi margaret,
    I am really enjoying reading your blogs for I have learned a lot of things from here. have a benign tumour behind my knee which is cannot be operable according to the surgeon. since 6 yrs ago, i have been eating tumeric powder…. 1/2 tablespoon a day.
    no effect on the tumor n its growing slowly from 1.5cm to 4.5cm.
    appreciate ur urgent advise what i should eat to shrink d tumour. GOD BLESS

    Reply
  170. Marie Maitre

    I have high blood pressure and a high cholesterol can I take turmeric with curcuming and what dose I should take

    Reply
    1. Flora Gadsn

      I have high blood pressure, high cholesterol, and suffer from constipation. Should I take curcumin2k and what dosage I should take?

      Reply
  171. Josephine Diagonale

    I have had an interesting side effect to taking first Doctor’s Best and now theracurmin. For years I have had a “trigger” right thumb. I have had cortisone shots and they did work. Then it all came back after a few years. The doctor now recommended a surgery to push the bone back into the socket. Well, I never had the surgery– I found curcumin instead. Trigger finger is all gone as are some of my ordinary aches and pains.

    I too have more energy and i also have some rash. I am still holding to my dose, however. Am just monitoring it all.

    Thanks for all your comments

    Reply
  172. Lorraine

    20.07.2014
    Hi, just discovered this site. What a huge amount of info! Thanks ever so much.
    Unfortunately I have quite a few health issues (not too strange for 70 yr old)
    1.Hiatus hernia, no gall bladder, zero oestrogen, No thyroid, taking Eltroxin, severe arthritis, using wheel chair, ulcer from taking anti-inflammatories for more than 30yrs! Stopped them. Pain unbearable. Any chance I can try Curcumin? Sip approx 500ml Apple Cider Vinegar, and make a fresh ginger tea every day, helps tremendously with reflux. Allergic to Codeine (perhaps just as well)! Any help out there. So sad to see so many folk with such serious problems. I had cancer 34 yrs ago, and still going!!!! I never stop thanking my Heavenly Father for His mercy. I live in South Africa!
    greetings and thanks L.

    Reply

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