Remember my posts on Jay Bradner and his Harvard team’s discovery…JQ1, the molecule that turns cancer cells into normal cells? if not, do a search of my blog…and look for my October/November 2011 posts. Well, we have a new Boston University (School of Medicine) study showing that JQ1 treatment dramatically reduces inflammatory responses in vitro and in vivo.
Here is the link to the abstract: http://goo.gl/Zed62. Now, even though I get reaaaaaally queasy now whenever I read about mice being injected with lethal substances and “sacrificed,” I couldn’t ignore the fact that 90% of JQ1-treated mice survived endotoxic shock while 0% survived in the non-treated group.
90% versus 0%.